IGF2 抗体 (AA 25-180)
Quick Overview for IGF2 抗体 (AA 25-180) (ABIN1098108)
抗原
See all IGF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 25-180
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原理
- IGF2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human IGF2 (AA: 25-180) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 16, Issue 4, pp. 346-54, (2011) (PubMed).
: "Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 2, pp. 339-45, (2011) (PubMed).
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: "Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 16, Issue 4, pp. 346-54, (2011) (PubMed).
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- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
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别名
- IGF2
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背景
- This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 20.1 kDa
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基因ID
- 3481
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UniProt
- P01344
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途径
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
抗原
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