PAX5 抗体 (AA 235-382)
(2 references)Quick Overview for PAX5 抗体 (AA 235-382) (ABIN1098104)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 235-382
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原理
- PAX5 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PAX5 (AA: 235-382) expressed in E. Coli.
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亚型
- IgG1
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anti-Paired Box 5 (PAX5) (AA 192-301) antibody
PAX5 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PAX5-3735 unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyVerified PAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Paired Box 5 (PAX5) (AA 178-207) antibodyPAX5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 217-282) antibodyPAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 362-391) antibodyPAX5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 192-302) antibodyPAX5 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) antibodyPAX5 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal rPAX5-2060 unconjugated Recombinant Antibody
anti-Paired Box 5 (PAX5) (N-Term) antibodyPAX5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease." in: Cancer research, Vol. 71, Issue 24, pp. 7345-50, (2011) (PubMed).
: "Expression profiling of transcription factors in B- or T-acute lymphoblastic leukemia/lymphoma and burkitt lymphoma: usefulness of PAX5 immunostaining as pan-Pre-B-cell marker." in: American journal of clinical pathology, Vol. 133, Issue 1, pp. 41-8, (2009) (PubMed).
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: "The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease." in: Cancer research, Vol. 71, Issue 24, pp. 7345-50, (2011) (PubMed).
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- PAX5 (Paired Box 5 (PAX5))
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别名
- PAX5
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背景
- This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
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分子量
- 45 kDa
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UniProt
- Q02548
抗原
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