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HNRNPA1 抗体

This anti-HNRNPA1 antibody is a 小鼠 单克隆 antibody detecting HNRNPA1 in WB, ELISA, IF, IP, ICC, IHC (p) 和 FACS. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 10+ publications.
产品编号 ABIN108609
发货至: 中国

Quick Overview for HNRNPA1 抗体 (ABIN108609)

抗原

See all HNRNPA1 抗体
HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

适用

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人, 小鼠

宿主

  • 82
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小鼠

克隆类型

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单克隆

标记

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This HNRNPA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

9H10
  • 纯化方法

    Protein A

    免疫原

    Full length hnRNP-A1 native protein (partially purified) from HeLa cells (human)

    亚型

    IgG2b
  • 应用备注

    Optimal antibody dilution should be determined by titration, however as a guideline try,Flow Cyt: Use 1 μg for 106 cells.IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocolWB: Use at 1:2000-1:4000. Detects a band of approximately 34 kDa (predicted molecular weight: 38 kDa)IP: Use at an assay dependent dilution. This antibody does not IP the hnRNP complex

    说明

    Myeloma, fusion partners: Balb/c Sp2/0 cell line

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Woolley, Algie, Samuel, Harfoot, Wiles, Hung, Tan, Hains, Valova, Huschtscha, Royds, Perez, Yoon, Cohen, Robinson, Bay, Lasham, Braithwaite: "Prognostic association of YB-1 expression in breast cancers: a matter of antibody." in: PLoS ONE, Vol. 6, Issue 6, pp. e20603, (2011) (PubMed).

    Beauchamp, Nassif, Hillock, van der Giessen, von Roretz, Jasmin, Gallouzi: "The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation." in: Cell death and differentiation, Vol. 17, Issue 10, pp. 1588-99, (2010) (PubMed).

    Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, (2010) (PubMed).

    Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, (2010) (PubMed).

    Sellier, Rau, Liu, Tassone, Hukema, Gattoni, Schneider, Richard, Willemsen, Elliott, Hagerman, Charlet-Berguerand: "Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients." in: The EMBO journal, Vol. 29, Issue 7, pp. 1248-61, (2010) (PubMed).

    Kocgozlu, Lavalle, Koenig, Senger, Haikel, Schaaf, Voegel, Tenenbaum, Vautier: "Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 29-39, (2009) (PubMed).

    Lieberthal, Kaminsky, Parkhurst, Tanese: "The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells." in: Breast cancer research : BCR, Vol. 11, Issue 3, pp. R42, (2009) (PubMed).

    Kashima, Rao, David, Manley: "hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing." in: Human molecular genetics, Vol. 16, Issue 24, pp. 3149-59, (2007) (PubMed).

    van der Giessen, Gallouzi: "Involvement of transportin 2-mediated HuR import in muscle cell differentiation." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2619-29, (2007) (PubMed).

    Burd, Dreyfuss: "RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing." in: The EMBO journal, Vol. 13, Issue 5, pp. 1197-204, (1994) (PubMed).

  • 抗原

    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

    别名

    hnRNP A1 

    背景

    Synonyms:
    HNRNPA 1 antibody,Helix destabilizing protein antibody,Helix-destabilizing proteinantibody,Heterogeneous nuclear ribonucleoprotein A1 antibody,Heterogeneous nuclear ribonucleoprotein A1B proteinantibody,Heterogeneous nuclear ribonucleoprotein B2 protein antibody,Heterogeneous nuclear ribonucleoprotein coreprotein A1 antibody,hnRNP A1 antibody,hnRNP core protein A1 antibody,HNRNPA1 antibody,HNRPA1antibody,MGC102835 antibody,Nuclear ribonucleoprotein particle A1 protein antibody,ROA1_HUMANantibody

    基因ID

    3178, 15382

    OMIM

    164017

    UniProt

    P09651, P49312
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