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SIP1 抗体 (AA 12-280)

This anti-SIP1 antibody is a 小鼠 单克隆 antibody detecting SIP1 in WB, ELISA, IF, IP, ICC 和 FACS. Suitable for 人, 小鼠 和 非洲爪蟾. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN108540
发货至: 中国

Quick Overview for SIP1 抗体 (AA 12-280) (ABIN108540)

抗原

See all SIP1 (GEMIN2) 抗体
SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

适用

  • 44
  • 30
  • 30
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 非洲爪蟾

宿主

  • 41
  • 4
小鼠

克隆类型

  • 41
  • 4
单克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIP1 antibody is un-conjugated

应用范围

  • 20
  • 14
  • 9
  • 9
  • 5
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

2E17
  • 抗原表位

    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-280

    纯化方法

    Protein A

    免疫原

    His-Gemin 2 fusion protein (amino acids 12 - 280, starting at 2nd methionine)

    亚型

    IgG1
  • 应用备注

    Optimal antibody dilution should be determined by titration, however as a guideline try:Flow Cyt: Use 1 μg for 106 cellWB: Use at an assay dependent dilution. Detects a band of approximately 34 kDa

    说明

    Myeloma, fusion partners: SP2/0

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Sanchez, Dury, Murray, Biondi, Tadesse, El Fatimy, Kothary, Charbonnier, Khandjian, Côté: "A novel function for the survival motoneuron protein as a translational regulator." in: Human molecular genetics, Vol. 22, Issue 4, pp. 668-84, (2013) (PubMed).

    Wu, Whye, Glazewski, Choe, Kerr, Lee, Mason, Wang: "Proteomic assessment of a cell model of spinal muscular atrophy." in: BMC neuroscience, Vol. 12, pp. 25, (2011) (PubMed).

    Takizawa, Qing, Takaku, Ishida, Morozumi, Tsujita, Kogame, Hirota, Takahashi, Shibata, Kurumizaka, Takeda: "GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination." in: Nucleic acids research, Vol. 38, Issue 15, pp. 5059-74, (2010) (PubMed).

    Burnett, Muñoz, Tandon, Kwon, Sumner, Fischbeck: "Regulation of SMN protein stability." in: Molecular and cellular biology, Vol. 29, Issue 5, pp. 1107-15, (2009) (PubMed).

    Walker, Rajendra, Saieva, Fuentes, Pellizzoni, Matera: "SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain." in: Human molecular genetics, Vol. 17, Issue 21, pp. 3399-410, (2008) (PubMed).

    Morency, Sabra, Catez, Texier, Lomonte: "A novel cell response triggered by interphase centromere structural instability." in: The Journal of cell biology, Vol. 177, Issue 5, pp. 757-68, (2007) (PubMed).

    Renvoisé, Khoobarry, Gendron, Cibert, Viollet, Lefebvre: "Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells." in: Journal of cell science, Vol. 119, Issue Pt 4, pp. 680-92, (2006) (PubMed).

    Liu, Fischer, Wang, Dreyfuss: "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins." in: Cell, Vol. 90, Issue 6, pp. 1013-21, (1997) (PubMed).

  • 抗原

    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

    别名

    Gemin 2

    背景

    Synonyms:
    Component of gems 2 antibody,GEMI2_HUMAN antibody,Gemin-2 antibody,gemin2 antibody,SIP 1antibody,SIP-1 antibody,SIP1 antibody,SIP1 delta antibody,SMN interacting protein 1 antibody,SMNinteracting protein 1 delta antibody,SMN-interacting protein 1 antibody,Survival interacting protein 1antibody,Survival of motor neuron protein interacting protein 1 antibody,Survival of motor neuronprotein-interacting protein 1 antibody

    基因ID

    8487

    OMIM

    602595

    途径

    Ribonucleoprotein Complex Subunit Organization, Tube Formation
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