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PABP 抗体

This 小鼠 单克隆 antibody specifically detects PABP in WB, ELISA, IF, IP, FACS 和 ICC. It exhibits reactivity toward 人, 兔, 小鸡, 非洲爪蟾 和 Hamster. It has been mentioned in 3+ publications
产品编号 ABIN108538
发货至: 中国
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Quick Overview for PABP 抗体 (ABIN108538)

抗原

See all PABP (PABPC1) 抗体
PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

适用

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人, 兔, 小鸡, 非洲爪蟾, Hamster

宿主

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小鼠

克隆类型

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单克隆

标记

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This PABP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

10E10
  • 纯化方法

    Protein G

    免疫原

    Recombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI

    亚型

    IgG2b
  • 应用备注

    Optimal antibody dilution should be determined by titration, however try:WB: Use at an assay dependent dilution. Detects a band of approximately 70 kDa (predicted molecular weight: 71 kDa)ICC/IF: Use at an assay dependent dilution. PubMed: 17977970Flow Cyt: Use 1 μg for 106 cells

    说明

    Myeloma, fusion partners: SP2/0

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Gorgoni, Richardson, Burgess, Anderson, Wilkie, Gautier, Martins, Brook, Sheets, Gray: "Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 19, pp. 7844-9, (2011) (PubMed).

    Unsworth, Raguz, Edwards, Higgins, Yagüe: "mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 9, pp. 3370-80, (2010) (PubMed).

    Görlach, Burd, Dreyfuss: "The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity." in: Experimental cell research, Vol. 211, Issue 2, pp. 400-7, (1994) (PubMed).

  • 抗原

    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

    别名

    PABP

    背景

    Synonyms:
    PAB 1 antibody,PAB1 antibody,PABP 1 antibody,PABP1 antibody,PABPC 1 antibody,PABPC1antibody,PABPC2 antibody,PABPL1 antibody,Poly A binding protein 1 antibody,Poly A binding protein cytoplasmic1 antibody,Polyadenylate binding protein 1 antibody

    基因ID

    117282

    OMIM

    604679

    UniProt

    P22626

    途径

    SARS-CoV-2 Protein Interactome
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