The antibody reacts with the aIIb-subunit of the b-integrins. Reacts specifically with platelets, megakaryocytes and leukemic cells able to megakaryocytic differentiation
免疫原
Monoclonal antibody to aIIb integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Partially purified platelet glycoprotein IIb/IIIa complex was used as an immunogen.