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SNCA 抗体 (AA 1-140)

There is 1 publication for this product available. The 兔 多克隆 anti-SNCA antibody is suitable to detect SNCA in samples from 人. It has been validated for WB, IHC, ICC 和 IP.
产品编号 ABIN1078556
发货至: 中国
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Quick Overview for SNCA 抗体 (AA 1-140) (ABIN1078556)

抗原

See all SNCA 抗体
SNCA (Synuclein, alpha (SNCA))

适用

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克隆类型

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多克隆

标记

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This SNCA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
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    AA 1-140

    原理

    Polyclonal Antibody to Synuclein Alpha (SNCa)

    序列

    MGHHHHHHSG SEFELRRQAC - MKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

    特异性

    The antibody is a rabbit polyclonal antibody raised against SNCa. It has been selected for its ability to recognize SNCa in immunohistochemical staining and western blotting.

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography

    免疫原

    Recombinant Synuclein Alpha (SNCa) corresdonding to Met1~Ala140 with N-terminal His Tag

    亚型

    IgG
  • 应用备注

    Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    说明

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

    储存液

    ProClin

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid repeated freeze/thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    有效期

    24 months
  • Bhattamisra, Shak, Xi, Safian, Choudhury, Lim, Shahzad, Alhakamy, Anwer, Radhakrishnan, Md: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." in: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).

  • 抗原

    SNCA (Synuclein, alpha (SNCA))

    别名

    SNCa

    背景

    SNC-A, aSYN, PD1, PARK1, PARK4, NACP, Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein, Non-A4 component of amyloid precursor

    途径

    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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