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CCL4 抗体

This anti-CCL4 antibody is a 兔 单克隆 antibody detecting CCL4 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1077439
发货至: 中国

Quick Overview for CCL4 抗体 (ABIN1077439)

抗原

See all CCL4 抗体
CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

适用

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人, 小鼠, 大鼠

宿主

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  • 3
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  • 1
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  • 1

克隆类型

  • 118
  • 14
单克隆

标记

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This CCL4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Rabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.

    亚型

    IgG
  • 应用备注

    CCL4 antibody can be used for detection of CCL4 by Western blot at 1 - 2 μg/mL.

    说明

    (IN) Chemokine (C-C motif) ligand 4

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    4 °C

    储存方法

    CCL4 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

    有效期

    12 months
  • 抗原

    CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

    别名

    CCL4

    背景

    CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.
    Synonyms: C-C motif ligand 4, macrophage inflammatory protein 1-beta, MIP1-beta, MIP1B, MIP1B1, ACT2, AT744.1, G-26, HC21, lymphocyte-activation gene 1, LAG-1, LAG1, SCYA2, SCYA4

    分子量

    10 kDa (calculated)

    基因ID

    6351

    NCBI登录号

    NP_002975
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