TPT1 抗体
Quick Overview for TPT1 抗体 (ABIN1077430)
抗原
See all TPT1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.
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亚型
- IgG
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应用备注
- TPT1 antibody can be used for detection of TPT1 by Western blot at 0.5 - 1 μg/mL.
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说明
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(IN) Translationally-controlled tumor protein 1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C
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储存方法
- TPT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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有效期
- 12 months
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- TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))
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别名
- TPT1
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背景
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TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Synonyms: Tumor protein translationally-controlled 1, translationally-controlled tumor protein, TCTP, fortilin, histamine-releasing factor, HRF, p23 -
分子量
- 19 kDa (calculated)
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基因ID
- 7178
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NCBI登录号
- NP_003286
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途径
- Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling
抗原
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