FOXP3 抗体 (C-Term)
Quick Overview for FOXP3 抗体 (C-Term) (ABIN1077427)
抗原
See all FOXP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
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亚型
- IgG
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应用备注
- FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.
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说明
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(CT) Forkhead box P3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C
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储存方法
- FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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有效期
- 12 months
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- FOXP3 (Forkhead Box P3 (FOXP3))
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别名
- FOXP3
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背景
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FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin -
分子量
- 47 kDa (calculated)
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基因ID
- 50943
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NCBI登录号
- NP_054728
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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