FOXP3 抗体 (C-Term)
Quick Overview for FOXP3 抗体 (C-Term) (ABIN1077427)
抗原
See all FOXP3 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            纯化方法
- Affinity chromatography purified via peptide column
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                                            免疫原
- Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
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                                            亚型
- IgG
 
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                                            应用备注
- FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.
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                                            说明
- 
                        (CT) Forkhead box P3 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- PBS containing 0.02 % Sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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                                            储存条件
- 4 °C
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                                            储存方法
- FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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                                            有效期
- 12 months
 
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    - FOXP3 (Forkhead Box P3 (FOXP3))
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                                            别名
- FOXP3
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                                            背景
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                        FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. 
 Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin
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                                            分子量
- 47 kDa (calculated)
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                                            基因ID
- 50943
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                                            NCBI登录号
- NP_054728
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                                            途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
 抗原
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