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FOXP3 抗体 (C-Term)

This anti-FOXP3 antibody is a 兔 单克隆 antibody detecting FOXP3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1077427
发货至: 中国

Quick Overview for FOXP3 抗体 (C-Term) (ABIN1077427)

抗原

See all FOXP3 抗体
FOXP3 (Forkhead Box P3 (FOXP3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This FOXP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.

    亚型

    IgG
  • 应用备注

    FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.

    说明

    (CT) Forkhead box P3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    4 °C

    储存方法

    FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

    有效期

    12 months
  • 抗原

    FOXP3 (Forkhead Box P3 (FOXP3))

    别名

    FOXP3

    背景

    FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
    Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin

    分子量

    47 kDa (calculated)

    基因ID

    50943

    NCBI登录号

    NP_054728

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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