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- 抗原 See all SHROOM1 抗体
- SHROOM1 (Shroom Family Member 1 (SHROOM1))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SHROOM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- SHROOM1 antibody is human, mouse and rat reactive. At least three isoforms of SHROOM1 are known to exist, this antibody will detect only the two largest isoforms. SHROOM1 antibody is predicted to not cross-react with other SHROOM family members.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal SHROOM1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SHROOM1.
- 亚型
- IgG
- Top Product
- Discover our top product SHROOM1 Primary Antibody
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- 应用备注
- SHROOM1 antibody can be used for detection of SHROOM1 by Western blot at 1 - 2 μg/mL.
- 说明
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(CT) SHROOM family member 1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- SHROOM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- SHROOM1 (Shroom Family Member 1 (SHROOM1))
- 别名
- SHROOM1 (SHROOM1 产品)
- 别名
- apx antibody, APXL2 antibody, 1300007L22Rik antibody, Apx antibody, Shrm1 antibody, RGD1308066 antibody, shrm antibody, shroom family member 1 antibody, shroom family member 1 L homeolog antibody, SHROOM1 antibody, shroom1 antibody, Shroom1 antibody, shroom1.L antibody
- 背景
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SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
Synonyms: SHROOM family member 1, Shroom, apical protein 2, APXL2 - 分子量
- 94 kDa
- 基因ID
- 134549
- NCBI登录号
- NP_001166171
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