Myc Target 1 抗体 (C-Term)
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- 抗原 See all Myc Target 1 (MYCT1) 抗体
- Myc Target 1 (MYCT1)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Myc Target 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
- 亚型
- IgG
- Top Product
- Discover our top product MYCT1 Primary Antibody
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- 应用备注
- MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- 说明
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(CT) Myc target protein 1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- MYCT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- Myc Target 1 (MYCT1)
- 别名
- MYCT1 (MYCT1 产品)
- 背景
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MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Synonyms: Myc target protein 1, myc target in myeloid cells 1, MTLC, MT-MC1 - 分子量
- 26 kDa
- 基因ID
- 80177
- NCBI登录号
- NP_079383
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