Myc Target 1 抗体 (C-Term)
Quick Overview for Myc Target 1 抗体 (C-Term) (ABIN1077374)
抗原
See all Myc Target 1 (MYCT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
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亚型
- IgG
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应用备注
- MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
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说明
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(CT) Myc target protein 1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C
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储存方法
- MYCT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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有效期
- 12 months
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- Myc Target 1 (MYCT1)
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别名
- MYCT1
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背景
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MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Synonyms: Myc target protein 1, myc target in myeloid cells 1, MTLC, MT-MC1 -
分子量
- 26 kDa
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基因ID
- 80177
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NCBI登录号
- NP_079383
抗原
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