Major Capsid Protein L1 抗体
适用: Human Papillomavirus (HPV)
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Major Capsid Protein L1
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适用
- Human Papillomavirus (HPV)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Caprylic Acid Ammonium Sulfate Precipitation
- 免疫原
- Recombinant HPV18 Major capsid protein L1 protein
- 亚型
- IgG
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- 应用备注
- Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Shipped at 4 °C. Upon delivery aliquot and store at -20 °C or -80 °C.
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- 抗原
- Major Capsid Protein L1
- 别名
- major capsid protein L1 antibody, L1 antibody
- 物质类
- Viral Protein
- 背景
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Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Synonyms: L1 - UniProt
- P06794
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