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SPRY2 抗体 (Internal Region)

This anti-SPRY2 antibody is a 兔 多克隆 antibody detecting SPRY2 in WB, ELISA, IHC, IF, FM 和 MA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
Rockland
产品编号 ABIN1043909
Supplier Product No.: 600-401-e68
发货至: 中国

Quick Overview for SPRY2 抗体 (Internal Region) (ABIN1043909)

抗原

See all SPRY2 抗体
SPRY2 (Sprouty Homolog 2 (SPRY2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPRY2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM), Multiplex Assay (MA)
  • 抗原表位

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    Internal Region

    Supplier Product No.

    600-401-e68

    Supplier

    Rockland

    原理

    Sprouty-2 Antibody

    交叉反应 (详细)

    Sprouty-2 antibody reacts with human Sprouty 2 protein.

    产品特性

    Synonyms: Rabbit anti-Sprouty2 antibody, Rabbit anti-Sprouty-2 antibody, Sprouty 2, SPRY2, SPRY 2, Spry-2, Protein sprouty homolog 2

    纯化方法

    Anti-Sprouty-2 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

    过滤

    Sterile filtered

    免疫原

    Immunogen: Anti-Sprouty-2 affinity purified antibody was purified from monospecific rabbit antiserum prepared via repeated immunizations with peptide corresponding to an internal region of human sprouty-2.

    Immunogen Type: Conjugated Peptide

    亚型

    IgG
  • 应用备注

    Immunohistochemistry Dilution: 10 μg/mL

    Application Note: Anti-Sprouty-2 antibody has been tested by ELISA, Immunofluorescence, Immunohistochemistry, and is suitable for western blotting. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:500-1:5,000

    ELISA Dilution: User Optimized

    IF Microscopy Dilution: User Optimized

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.04 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • Zhang, Chaturvedi, Jaggar, Magnuson, Lee, Patel: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).

    August: "Cerebrovascular and carotid artery disease." in: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).

  • 抗原

    SPRY2 (Sprouty Homolog 2 (SPRY2))

    别名

    SPRY2

    背景

    Background: Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty-2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C-terminus of the protein. Significant sequence divergence occurs at the N-terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.

    基因ID

    10253

    UniProt

    O43597

    途径

    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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