Glycogen Synthase 1 抗体 (pSer641)
(1 reference)
Quick Overview for Glycogen Synthase 1 抗体 (pSer641) (ABIN1043894)
抗原
See all Glycogen Synthase 1 (GYS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer641
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Supplier Product No.
- 600-401-b28
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Supplier
- Rockland
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原理
- Muscle Glycogen Synthase Phospho S641 Antibody
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交叉反应 （详细）
- Phospho Glycogen Synthase pS641 antibody is directed against human muscle glycogen synthase.
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产品特性
- Synonyms: rabbit anti-muscle glycogen synthase pS641 antibody, rabbit anti-glycogen synthase pS641 antibody, Glycogen antibody, Glycogen synthase 1 (muscle) antibody, Glycogen synthase 1 antibody, Glycogen synthase1 antibody, GYS 1 antibody, GYS-1 antibody, GYS1 antibody, Starch synthase muscle antibody
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Human Muscle Glycogen Synthase phospho peptide corresponding to pS641 region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Glycogen Synthase 1 (Muscle) (GYS1) (AA 488-737) antibody
GYS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) antibodyGYS1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 10C1 unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer645) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (C-Term) antibodyGYS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1D1 unconjugated Recombinant Antibody
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibodyGYS1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer645) antibodyGYS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer645) antibodyGYS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: 1:1,000 - 1:5,000
Application Note: This phospho specific polyclonal antibody was tested by immunohistochemistry, immunoblotting, and ELISA. By ELISA the antibody was found to be reactive with the phosphorylated form of the immunizing peptide and minimally reactive with the non-phosphorylated form of the immunizing peptide. Immunoblotting will detect human and mouse muscle glycogen synthase. Although not tested, this antibody is likely functional in immunoprecipitation.
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:5,000 - 1:25,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store Phospho GYS1 antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals." in: Journal of neurochemistry, Vol. 118, Issue 4, pp. 596-610, (2011) (PubMed).
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: "R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals." in: Journal of neurochemistry, Vol. 118, Issue 4, pp. 596-610, (2011) (PubMed).
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- Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
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别名
- GYS1
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背景
- Background: Anti-Glycogen Synthase 1 pS641 antibody is validated by IHC, Western Blot and ELISA. Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephosphorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3β that mainly functions to phosphorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at S641. Phosphorylation of GS at S641 has been associated with Antiphospholipid Antibody Syndrome.
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基因ID
- 2997
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UniProt
- P13807
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途径
- PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
抗原
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