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IL-25 抗体

Cited in 1 publication. This anti-IL-25 antibody is a 小鼠 单克隆 antibody detecting IL-25 in WB, ELISA 和 FACS. Suitable for 人.
Rockland
产品编号 ABIN1043787
Supplier Product No.: 209-301-c58
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-25 抗体 (ABIN1043787)

抗原

See all IL-25 (IL25) 抗体
IL-25 (IL25) (Interleukin 25 (IL25))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-25 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

11K8B1
  • Supplier Product No.

    209-301-c58

    Supplier

    Rockland

    原理

    IL-17E Antibody

    交叉反应 (详细)

    This antibody is specific for human IL-17E protein.

    产品特性

    Synonyms: mouse Anti-IL-17E Antibody, mouse anti-IL-25 antibody, Interleukin 25, IL-25, Interleukin 17E, IL-17E

    纯化方法

    Anti-IL-17E was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.

    过滤

    Sterile filtered

    免疫原

    Immunogen: Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    亚型

    IgG1
  • 应用备注

    Flow Cytometry Dilution: 1 μg/mL

    Application Note: IL 17E antibody has been tested for use in Flow Cytometry and western blotting. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 0.5 μg/mL

    ELISA Dilution: 1:10,000-1:50,000

    Other: User Optimized

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • Conti, Shen, Nayyar, Stocum, Sun, Lindemann, Ho, Hai, Yu, Jung, Filler, Masso-Welch, Edgerton, Gaffen: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).

  • 抗原

    IL-25 (IL25) (Interleukin 25 (IL25))

    别名

    IL25

    背景

    Background: Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.

    基因ID

    64806

    NCBI登录号

    NP_073626

    UniProt

    Q9H293
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