IL17F 抗体
(1 reference)
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北京 101111
Quick Overview for IL17F 抗体 (ABIN1043779)
抗原
See all IL17F 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 209-301-b31
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Supplier
- Rockland
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原理
- IL-17F Antibody
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交叉反应 （详细）
- This antibody is specific for human IL-17F protein.
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产品特性
- Synonyms: mouse anti-IL-17F antibody, mouse anti-Interleukin-17F antibody, Cytokine ML-1, Interleukin-24
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纯化方法
- Anti-Human IL-17F (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Immunogen Type: Recombinant Protein
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亚型
- IgG1
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anti-Interleukin 17F (IL17F) (AA 1-163) antibody
IL17F 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 1-163) antibodyIL17F 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) antibodyIL17F 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 31-163) antibodyIL17F 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated
anti-Interleukin 17F (IL17F) (Internal Region) antibodyIL17F 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 31-140) antibodyIL17F 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Interleukin 17F (IL17F) antibody (Biotin)IL17F 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 17F (IL17F) (AA 16-45) antibodyIL17F 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) antibody (Biotin)IL17F 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H1629-1 Biotin
anti-Interleukin 17F (IL17F) (AA 31-163) antibodyIL17F 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: 5 μg/mL
Application Note: Anti-Human IL-17F antibody has been tested for use in IHC and Western Blot. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 0.5 μg/mL
ELISA Dilution: 1:10,000-1:50,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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- IL17F (Interleukin 17F (IL17F))
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别名
- IL17F
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背景
- Background: Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.
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基因ID
- 112744
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NCBI登录号
- NP_443104
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UniProt
- Q96PD4
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
抗原
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