BIN3 抗体
(1 reference)
Quick Overview for BIN3 抗体 (ABIN1043741)
抗原
See all BIN3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-e64
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Supplier
- Rockland
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原理
- BIN3 Antibody
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交叉反应 （详细）
- BIN3 antibody is specific for human BIN3 protein.
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产品特性
- Synonyms: mouse anti-BIN3 Antibody, Bridging integrator 3, BIN-3, BIN 3, BIN3 antibody, anti-BIN-3 antibody
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纯化方法
- Anti-BIN3 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full length human BIN3 recombinant protein followed by hybridoma development.
Immunogen Type: Recombinant Protein
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亚型
- IgG1
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anti-Bridging Integrator 3 (BIN3) antibody
BIN3 适用: 人, 犬, 猴 WB, FACS, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E9 unconjugated
anti-Bridging Integrator 3 (BIN3) antibodyBIN3 适用: 人, 大鼠, 犬, 猴 WB, FACS, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5E3 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 154-253) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 8-240) antibodyBIN3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) antibodyBIN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-199) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-199) antibodyBIN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-200) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-253) antibodyBIN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-30), (N-Term) antibodyBIN3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21391 unconjugated
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应用备注
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Application Note: Anti-BIN3 antibody has been tested for use in ELISA, Western Blot, and IP. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:500-1:1500
Immunoprecipitation Dilution: 10-100 μL
ELISA Dilution: 1:5000-1:50000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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- BIN3 (Bridging Integrator 3 (BIN3))
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别名
- BIN3
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背景
- Background: BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin's lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
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基因ID
- 55909
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NCBI登录号
- NP_061158
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UniProt
- Q9NQY0
抗原
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