gamma-Tubulin GCP2 (AA 2-194) 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in ICC, IHC (p), IP 和 WB. Suitable for 人, 小鼠, Pig 和 大鼠. This Primary Antibody has been cited in 2+ publications.
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(2 references)Quick Overview for gamma-Tubulin GCP2 (AA 2-194) 抗体 (ABIN1043030)
抗原
gamma-Tubulin GCP2
适用
人, 小鼠, Pig, 大鼠
宿主
小鼠
克隆类型
单克隆
应用范围
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
GCP2-01
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抗原表位
- AA 2-194
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原理
- Anti-gamma-Tubulin GCP2 Purified
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特异性
- The mouse monoclonal antibody GCP2-01 recognizes gamma-tubulin complex component 2 (GCP2), a 95-103 kDa intracellular protein. It recognizes also phosphorylated GCP2.
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交叉反应 （详细）
- Human, Porcine, Mouse, Rat
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- GST-fusion protein containing amino acids 2-194 of mouse GCP2
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亚型
- IgG2b kappa
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应用备注
- Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Overexpression and Nucleolar Localization of ?-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 7, pp. 723-42, (2015) (PubMed).
: "Nuclear ?-tubulin associates with nucleoli and interacts with tumor suppressor protein C53." in: Journal of cellular physiology, Vol. 227, Issue 1, pp. 367-82, (2011) (PubMed).
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: "Overexpression and Nucleolar Localization of ?-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 7, pp. 723-42, (2015) (PubMed).
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- gamma-Tubulin GCP2
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背景
- Tubulin gamma complex associated protein 2,Gamma tubulin complex component 2 (GCP2) is 95-103 kDa protein which associates with two molecules of gamma tubulin and one molecule of gamma tubulin complex component 3 (GCP3), to form the gamma tubulin small complexes (gammaTuSCs). These complexes interact with GCP4, 5, and 6 to form the gamma tubulin ring complexes (gammaTuRCs), which are embedded in the microtubule organizing center matrix where they nucleate microtubules. The gammaTuRCs are also involved in the regulation of microtubule plus and minus end dynamics. Components of gamma tubulin complexes are highly conservative in eukaryotes.,GCP-2, GTCC2, GTC2
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基因ID
- 10844
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UniProt
- Q9BSJ2
抗原
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