VGlut2 Transporter (AA 501-582), (C-Term) 抗体
This 小鼠 单克隆 antibody specifically detects VGlut2 Transporter in IHC, WB 和 IF/ICC. It exhibits reactivity toward 大鼠.
产品编号 ABIN1043020
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for VGlut2 Transporter (AA 501-582), (C-Term) 抗体 (ABIN1043020)
抗原
VGlut2 Transporter
适用
大鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)
克隆位点
S29-29
-
-
抗原表位
- AA 501-582, C-Term
-
原理
- Anti-VGlut2 Transporter Mouse Monoclonal Antibody
-
特异性
- This antibody recognizes human, mouse, and rat VGlut2.
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein G affinity chromatography.
-
免疫原
- Fusion protein corresponding to aa 501-582 (cytoplasmic C-terminus) of rat VGlut2 (accession no. NP_445879).
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunoblotting: use at 1-2 μg/mL. A band of ~60 kDa is detected.
Immunohistochemistry: use at 1-5 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their applications.
Positive control: rat brain lysate. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
-
-
- VGlut2 Transporter
-
背景
- Vesicular glutamate transporter 2,Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:11551935, PubMed:11698619, PubMed:11698620, PubMed:11502256, PubMed:17046815, PubMed:18080752). May also mediate the transport of inorganic phosphate (PubMed:17046815). Involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity). May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas (PubMed:11551935). {UniProtKB:Q8BLE7, PubMed:11502256, PubMed:11551935, PubMed:11698619, PubMed:11698620, PubMed:17046815, PubMed:18080752}.,The ATP-dependent, chloride-sensitive vesicular glutamate transporters include VGlut1, VGlut2, and VGlut3. VGlut1 and VGlut2 are expressed in brain in a complementary fashion. VGlut1 is expressed in the telencephalic regions whereas VGlut2 is expressed in the lower brainstem and diencephalic regions. VGlut3 is expressed in a small number of neurons in the striatum, hippocampus, cerebral cortex, and raphe nuclei. Pancreatic alpha and beta cells express VGlut1 and VGlut2 in response to glucose concentrations.,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Cell junction, synapse, synaptosome,VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6
-
UniProt
- Q9JI12
抗原
-
You are here:
