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Progerin (AA 604-611) 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-Progerin antibody is suitable to detect Progerin in samples from 人. It has been validated for ICC, IF, WB, IP 和 ELISA.
产品编号 ABIN1042661
发货至: 中国
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Quick Overview for Progerin (AA 604-611) 抗体 (ABIN1042661)

抗原

Progerin

适用

宿主

小鼠

克隆类型

单克隆

应用范围

Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB), Immunoprecipitation (IP), ELISA

克隆位点

13A4D4
  • 抗原表位

    AA 604-611

    序列

    GAQSPQNC

    特异性

    Specifically recognizes Progerin (LaminAdelta50) and does not cross-react with endogenous prelamin A

    纯化方法

    Protein G

    免疫原

    Synthetic peptide conjugated to KLH derived from within residues 604 - 611 (GAQSPQNC) at the C terminus of Human Progerin

    亚型

    IgG1 kappa
  • 应用备注

    Optimal antibody dilution should be determined by titration, however as a guideline try,WB: 1/500. Detects a band of approximately 70 kDa

    说明

    Myeloma, fusion partners: X63-Ag8.653

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Liu, Barkho, Ruiz, Diep, Qu, Yang, Panopoulos, Suzuki, Kurian, Walsh, Thompson, Boue, Fung, Sancho-Martinez, Zhang, Yates, Izpisua Belmonte: "Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome." in: Nature, Vol. 472, Issue 7342, pp. 221-5, (2011) (PubMed).

  • 抗原

    Progerin

    别名

    Progerin 

    基因ID

    24380

    OMIM

    150330
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