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DGKA 抗体

Cited in 1 publication. The 小鼠 单克隆 anti-DGKA antibody (Clone M6) (ABIN1042452) specifically detects DGKA in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN1042452
发货至: 中国
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Quick Overview for DGKA 抗体 (ABIN1042452)

抗原

See all DGKA 抗体
DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DGKA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

M6
  • 特异性

    M6 is directed against the C-terminal portion (part of the catalytic domain) of rat DGKa.

    产品特性

    Other

    纯化方法

    Purified
  • 应用备注

    M6 is useful for immunoprecipitation and western blot. Optimal antibody dilution should be determined by titration.

    说明

    M6 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of rat DGKu.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.09% sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Guckes, McCarthy, Brahim: "Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow-up." in: Pediatric dentistry, Vol. 19, Issue 4, pp. 282-5, (1997) (PubMed).

  • 抗原

    DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

    别名

    DGKa

    背景

    Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.
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