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AFAP1L1 抗体 (N-Term)

This anti-AFAP1L1 antibody is a 兔 多克隆 antibody detecting AFAP1L1 in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN1031218
发货至: 中国

Quick Overview for AFAP1L1 抗体 (N-Term) (ABIN1031218)

抗原

See all AFAP1L1 抗体
AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

适用

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人, 小鼠

宿主

  • 12

克隆类型

  • 12
多克隆

标记

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This AFAP1L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    AFAP1L1 antibody was raised against a AA 19 synthetic peptide near the amino terminus of human AFAP1L1.

    亚型

    IgG
  • 应用备注

    AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    4 °C/-20 °C

    储存方法

    AFAP1L antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.

    有效期

    12 months
  • 抗原

    AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

    背景

    Synonym:
    Actin filament associated protein 1-like 1

    The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation . Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.

    基因ID

    134265

    NCBI登录号

    NP_689619
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