AFAP1L1 抗体 (N-Term)
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Quick Overview for AFAP1L1 抗体 (N-Term) (ABIN1031218)
抗原
See all AFAP1L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- AFAP1L1 antibody was raised against a AA 19 synthetic peptide near the amino terminus of human AFAP1L1.
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亚型
- IgG
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应用备注
- AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C/-20 °C
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储存方法
- AFAP1L antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.
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有效期
- 12 months
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- AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))
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背景
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Synonym:
Actin filament associated protein 1-like 1
The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation . Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas. -
基因ID
- 134265
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NCBI登录号
- NP_689619
抗原
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