ABCC8 抗体 (AA 1548-1582)
Quick Overview for ABCC8 抗体 (AA 1548-1582) (ABIN1027723)
抗原
See all ABCC8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1548-1582
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特异性
- Detects ~160 kDa. Does not cross-react with SUR2B.
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交叉反应
- Hamster, 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1
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亚型
- IgG1
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 679-929) antibody
ABCC8 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (HRP)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 HRP
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (FITC)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 FITC
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Biotin)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Biotin
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (PE)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 PE
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (PerCP)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 PerCP
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (APC)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 APC
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Atto 488)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 488
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Atto 594)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 594
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Atto 390)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 390
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应用备注
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN1027723 was sufficient for detection of SUR1 in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
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别名
- SUR1
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背景
- Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2) (1). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6.x potassium channel. Hence the KATP channel monitors the energy balance within the cell (2).
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基因ID
- 25559
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NCBI登录号
- NP_037171
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UniProt
- Q09429
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途径
- Negative Regulation of Hormone Secretion
抗原
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