N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH) 抗体
Cited in 6+ publications.
The Human 单克隆 anti-N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH) antibody (Clone 5F12) (ABIN1020378) specifically detects N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH) in IHC 和 ELISA.
The antibody is reactive with Keyhole Limpet samples.
(6 references)
产品编号 ABIN1020378
发货至:
中国
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Quick Overview for N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH) 抗体 (ABIN1020378)
抗原
N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH)
适用
Keyhole Limpet
宿主
Human, 大鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (IHC), ELISA
克隆位点
5F12
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特异性
- Specific to Hexanoyl-Lys adducts.
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亚型
- IgG1 kappa
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应用备注
- Recommended antibody concentration is 2 µg/mL on paraformaldehyde fixed tissue.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Containing 10mM PBS(pH7.4), 5% sucrose, 1% BSA and 0.05% Procline 950. 100 µg/mL of IgG.
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储存液
- ProClin
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储存条件
- -20 °C
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: "Expressions of lipid oxidation markers, N(ε)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 73, Issue 6, pp. 821-6, (2011) (PubMed).
: "Evaluation of therapeutic effects of astaxanthin on impairments in salivary secretion." in: Journal of clinical biochemistry and nutrition, Vol. 47, Issue 2, pp. 130-7, (2010) (PubMed).
: "Evaluation of lipid oxidative stress status and inflammation in atopic ocular surface disease." in: Molecular vision, Vol. 16, pp. 2465-75, (2010) (PubMed).
: "Immunohistochemical detection of oxidative stress biomarkers, dityrosine and N(epsilon)-(hexanoyl)lysine, and C-reactive protein in rabbit atherosclerotic lesions." in: Journal of atherosclerosis and thrombosis, Vol. 15, Issue 4, pp. 185-92, (2008) (PubMed).
: "Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress." in: Stroke; a journal of cerebral circulation, Vol. 36, Issue 3, pp. 670-2, (2005) (PubMed).
: "Increase in oxidative stress in kidneys of diabetic Akita mice." in: Bioscience, biotechnology, and biochemistry, Vol. 66, Issue 4, pp. 869-72, (2002) (PubMed).
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: "Expressions of lipid oxidation markers, N(ε)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 73, Issue 6, pp. 821-6, (2011) (PubMed).
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- N epsilon Hexanoyl-Keyhole Limpet Hemocyanin (HEL-KLH)
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背景
- Oxidative damage of lipids caused by reactive oxygen species (ROS) play an important role in some diseases, lesion of cell functions and aging. Aldehydes such as malondi-aldehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) have been reported as one of the advanced lipid peroxidation products. But recently in the earlier stage of lipid peroxidation, 13-hydroperoxyoctadecanoic acid (13-HPODE) is found to be covalently bound to proteins1). Hexanoyl-Lysine adduct (HEL) is a novel lipid hydroperoxide-modified lysine residues. HEL is formed by oxidative modification by oxidized omega-6 fatty acids such as linoleic acid or arachidonic acid. This monoclonal antibody (clone 5H4)is spesific for proteins and peptides containing HEL. Suitable for HEL detection by immunohistochemistry and western blotting.
抗原
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