HIF3A 抗体 (AA 575-600)
(1 reference)
Quick Overview for HIF3A 抗体 (AA 575-600) (ABIN100475)
抗原
See all HIF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 575-600
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Supplier Product No.
- 600-401-435
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Supplier
- Rockland
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原理
- Hif3 alpha Antibody
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交叉反应 （详细）
- This affinity-purified antibody is directed against mouse Hif3alpha protein.
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产品特性
- Synonyms: rabbit anti-Hif3a antibody, Hif3 alpha antibody, Hif3α antibody, Hypoxia Inducible Factor 3-alpha antibody, Hypoxia inducible factor 3 alpha subunit antibody, Inhibitory PAS domain protein antibody, IPAS antibody, HIF-3-alpha, Basic-helix-loop-helix-PAS protein MOP7, HIF3-alpha-1, Neonatal and embryonic PAS protein
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 575-600 of mouse Hif3 a (Hypoxia Inducible Factor).
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) antibody
HIF3A 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 581-592) antibodyHIF3A 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 516-669) antibodyHIF3A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 1-669) antibodyHIF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 355-669) antibodyHIF3A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (C-Term) antibodyHIF3A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (C-Term) antibodyHIF3A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (N-Term) antibodyVerified HIF3A 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 1-363) antibodyHIF3A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (Internal Region) antibodyHIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity-purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 72 kDa in size corresponding to Hif3 alpha protein by western blotting in the appropriate cell lysate or extract. This antibody is expected to cross-react with mouse and rat Hif3 alpha due to sequence homology.
Western Blot Dilution: 1:1,000 - 1:8,000
ELISA Dilution: 1:14,000 - 1:80,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8336-46, (2006) (PubMed).
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: "Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8336-46, (2006) (PubMed).
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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别名
- Hif3a
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背景
- Background: One of the most important factors in the cellular response to hypoxia is hypoxia-inducible factor (HIF), which transcriptionally activates genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a member of the basic helix-loop-helix (bHLH) superfamily, in which the HLH domain mediates subunit dimerization while the basic domain binds to DNA. HIF binds to the hypoxia-responsive elements (HRE) located within the enhancer/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation, and cell survival, in fact, HIF3-a may be a marker for tumor growth and apoptosis. Hif3 may participate in disorders with the cornea, lung, and heart. Anti-Hif3 alpha Antibody is useful for researchers interested in transcription factors, DNA binding, and Epilepsy research.
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基因ID
- 53417, 170295859
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UniProt
- Q0VBL6
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途径
- Warburg Effect
抗原
-
