Rhinovirus 16 抗体
适用: Human Rhinovirus (HRV)
IHC, WB
宿主: 小鼠
Monoclonal
R16-7
unconjugated
(4 references)-
- 抗原
- Rhinovirus 16
- 适用
- Human Rhinovirus (HRV)
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
- 应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 原理
- Anti-Rhinovirus 16 Mouse Monoclonal Antibody
- 特异性
- This non-neutralizing antibody recognizes capsid protein VP2 (mw ~30 kDa) of HRV16, HRV1A, and HRV39 and VP2 precursors VP0 (mw ~37 kDa) and P1 (mw ~90 kDa).
- 交叉反应
- Human Rhinovirus (HRV)
- 免疫原
- Purified HRV16.
- 克隆位点
- R16-7
- 亚型
- IgG2b
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- 应用备注
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Immunoblotting: use at 2-5 μg/mL.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations,
Endusers should determine optimal concentrations for their applications. - 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- This antibody is stable for at least one (1) year at -20°C.
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: "Microglia HMC3 cells are highly susceptible to Rhinovirus infection." in: Virus research, Vol. 288, pp. 198110, (2020) (PubMed).
: "Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells." in: PLoS ONE, Vol. 14, Issue 2, pp. e0210702, (2019) (PubMed).
: "Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP." in: PLoS ONE, Vol. 12, Issue 11, pp. e0188010, (2017) (PubMed).
: "The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19681-96, (2015) (PubMed).
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: "Microglia HMC3 cells are highly susceptible to Rhinovirus infection." in: Virus research, Vol. 288, pp. 198110, (2020) (PubMed).
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- 抗原
- Rhinovirus 16
- 物质类
- Virus
- 背景
- Picornaviruses are small, non-enveloped RNA viruses with an icosahedral capsid and a single strand, plus-sense RNA genome. The genome encodes a single polyprotein that is proteolytically processed by viral proteases into structural and non-structural proteins. The family of picornaviruses includes numerous human and animal viruses including more than 100 s of human rhinoviruses (HRV). HRV infections are characteristic upper airway infections (the main cause of the common cold), and they provoke significant lower airway symptoms for patients with asthma, cystic fibrosis, or chronic obstructive pulmonary disease.
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