ANTXR1 抗体
(anthrax Toxin Receptor 1 (ANTXR1))
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008].
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Latest Publications for our ANTXR1 抗体
: "Isolated tumor endothelial cells maintain specific character during long-term culture." in: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 947-54, (2010) (PubMed).: "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin." in: Cell, Vol. 124, Issue 6, pp. 1141-54, (2006) (PubMed).
: "Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23227-36, (2006) (PubMed).
: "Receptor-specific requirements for anthrax toxin delivery into cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13278-83, (2005) (PubMed).
: "TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen." in: Experimental cell research, Vol. 305, Issue 1, pp. 133-44, (2005) (PubMed).
: "TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)." in: Cancer research, Vol. 64, Issue 3, pp. 817-20, (2004) (PubMed).
: "Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48404-9, (2001) (PubMed).
: "Mitochondrial endonuclease G is important for apoptosis in C. elegans." in: Nature, Vol. 412, Issue 6842, pp. 90-4, (2001) (PubMed).
: "Apoptosis. Till death us do part." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).
: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).
Aliases for ANTXR1 抗体
anthrax toxin receptor 1 (ANTXR1) 抗体anthrax toxin receptor 1 (Antxr1) 抗体
2310008J16Rik 抗体
2810405N18Rik 抗体
Antrx1 抗体
ANTXR1 抗体
ATR 抗体
TEM8 抗体
Tem8 抗体
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