ANGL4 Protein (AA 28-403, partial) (GST tag)
This Recombinant ANGL4 protein is expressed in 大肠杆菌（E. Coli）.
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产品编号 ABIN5712720
发货至:
中国
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中国
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Quick Overview for ANGL4 Protein (AA 28-403, partial) (GST tag) (ABIN5712720)
抗原
ANGL4
(Angiopoietin-Related Protein 4 (ANGL4))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
SDS-PAGE (SDS)
纯度
Greater than 90 % as determined by SDS-PAGE.
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产品特性
- AA 28-403, partial
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标记
- This ANGL4 protein is labelled with GST tag.
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原理
- Recombinant Human Angiopoietin-related protein 4(ANGPTL4),partial
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序列
- VQSKSPRFAS WDEMNVLAHG LLQLGQGLRE HAERTRSQLS ALERRLSACG SACQGTEGST DLPLAPESRV DPEVLHSLQT QLKAQNSRIQ QLFHKVAQQQ RHLEKQHLRI QHLQSQFGLL DHKHLDHEVA KPARRKRLPE MAQPVDPAHN VSRLHRLPRD CQELFQVGER QSGLFEIQPQ GSPPFLVNCK MTSDGGWTVI QRRHDGSVDF NRPWEAYKAG FGDPHGEFWL GLEKVHSITG DRNSRLAVQL RDWDGNAELL QFSVHLGGED TAYSLQLTAP VAGQLGATTV PPSGLSVPFS TWDQDHDLRR DKNCAKSLSG GWWFGTCSHS NLNGQYFRSI PQQRQKLKKG IFWKTWRGRY YPLQATTMLI QPMAAE
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产品特性
- N-terminal GST-tagged
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- Tris-based buffer50 % glycerol
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储存条件
- -20 °C,-80 °C
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储存方法
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
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有效期
- 6-12 months
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- ANGL4 (Angiopoietin-Related Protein 4 (ANGL4))
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别名
- ANGL4
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背景
- Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
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分子量
- 69.6 kDa
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基因ID
- 51129
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UniProt
- Q9BY76
抗原
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