Alkaline Phosphatase, Liver/bone/kidney 抗体
(Alkaline Phosphatase, Liver/bone/kidney (ALPL))
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ALPL 抗体 (AA 18-335) | Cow | 兔 Polyclonal |
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| ALPL 抗体 | 人 | 小鼠 Monoclonal |
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| ALPL 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 | 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 (AA 28-501) (Biotin) | 小鼠 | 兔 Polyclonal |
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| ALPL 抗体 (Biotin) | 小鼠 | 兔 Polyclonal |
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| ALPL 抗体 (N-Term) | 人, 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 (AA 20-503) (FITC) | 小鼠 | 兔 Polyclonal |
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| ALPL 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| ALPL 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| ALPL 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| ALPL 抗体 (Alexa Fluor 647) | 人 | 兔 Polyclonal |
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| Recombinant ALPL 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| ALPL 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| ALPL 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| ALPL 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 | 人 | 小鼠 Monoclonal |
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| ALPL 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ALPL 抗体 (Center) | 人, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- Cow
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 18-335
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 28-501
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 20-503
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Latest Publications for our Alkaline Phosphatase, Liver/bone/kidney 抗体
: "Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration." in: Cell stem cell, Vol. 24, Issue 2, pp. 240-256.e9, (2019) (PubMed).
: "Activation of cancer-related and mitogen-activated protein kinase signaling pathways in human mature osteoblasts isolated from patients with type 2 diabetes." in: Bone reports, Vol. 10, pp. 100199, (2019) (PubMed).
: "Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells." in: International journal of molecular sciences, Vol. 20, Issue 5, (2019) (PubMed).
: "Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ." in: Scientific reports, Vol. 9, Issue 1, pp. 6688, (2019) (PubMed).
: "Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs." in: Carcinogenesis, (2019) (PubMed).
: "Multicolor quantitative confocal imaging cytometry." in: Nature methods, Vol. 15, Issue 1, pp. 39-46, (2018) (PubMed).
: "Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 1086-1096, (2018) (PubMed).
: "Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia." in: Theranostics, Vol. 8, Issue 20, pp. 5575-5592, (2018) (PubMed).
: "Development of a micro-tissue-mediated injectable bone tissue engineering strategy for large segmental bone defect treatment." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 331, (2018) (PubMed).
: "Morphological and functional analyses of skeletal muscles from an immunodeficient animal model of limb-girdle muscular dystrophy type 2E." in: Muscle & nerve, (2018) (PubMed).
: "Activation of cancer-related and mitogen-activated protein kinase signaling pathways in human mature osteoblasts isolated from patients with type 2 diabetes." in: Bone reports, Vol. 10, pp. 100199, (2019) (PubMed).
: "Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells." in: International journal of molecular sciences, Vol. 20, Issue 5, (2019) (PubMed).
: "Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ." in: Scientific reports, Vol. 9, Issue 1, pp. 6688, (2019) (PubMed).
: "Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs." in: Carcinogenesis, (2019) (PubMed).
: "Multicolor quantitative confocal imaging cytometry." in: Nature methods, Vol. 15, Issue 1, pp. 39-46, (2018) (PubMed).
: "Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 1086-1096, (2018) (PubMed).
: "Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia." in: Theranostics, Vol. 8, Issue 20, pp. 5575-5592, (2018) (PubMed).
: "Development of a micro-tissue-mediated injectable bone tissue engineering strategy for large segmental bone defect treatment." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 331, (2018) (PubMed).
: "Morphological and functional analyses of skeletal muscles from an immunodeficient animal model of limb-girdle muscular dystrophy type 2E." in: Muscle & nerve, (2018) (PubMed).
Aliases for Alkaline Phosphatase, Liver/bone/kidney 抗体
alkaline phosphatase, liver/bone/kidney (ALPL) 抗体alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L) 抗体
alkaline phosphatase, liver/bone/kidney (Alpl) 抗体
alkaline phosphatase, intestinal, gene 2 (alpi.2) 抗体
Akp-2 抗体
Akp2 抗体
ALP 抗体
alpl 抗体
AP-TNAP 抗体
APTNAP 抗体
HOPS 抗体
iap 抗体
PHOA 抗体
TNAP 抗体
TNS-AP 抗体
TNSALP 抗体
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