ALIX 抗体
(Programmed Cell Death 6 Interacting Protein (PDCD6IP))
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012].
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86 results
PDCD6IP
适用: 人, 小鼠, 大鼠
WB, IHC, IF, ICC, FACS
宿主: 小鼠
Monoclonal
14D10
unconjugated
Latest Publications for our ALIX 抗体
: "Proteomic Characterization of Epithelial-Like Extracellular Vesicles in Advanced Endometrial Cancer." in: Journal of proteome research, Vol. 18, Issue 3, pp. 1043-1053, (2019) (PubMed).: "Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells." in: PLoS pathogens, Vol. 15, Issue 7, pp. e1007907, (2019) (PubMed).
: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).
: "Extracellular Vesicles from Bone Marrow-Derived Mesenchymal Stem Cells Improve Survival from Lethal Hepatic Failure in Mice." in: Stem cells translational medicine, Vol. 6, Issue 4, pp. 1262-1272, (2017) (PubMed).
: "MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method." in: The Prostate, Vol. 77, Issue 10, pp. 1167-1175, (2017) (PubMed).
: "Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 8, pp. E968-77, (2016) (PubMed).
: "Structural Analysis of the Complex between Penta-EF-Hand ALG-2 Protein and Sec31A Peptide Reveals a Novel Target Recognition Mechanism of ALG-2." in: International journal of molecular sciences, Vol. 16, Issue 2, pp. 3677-99, (2015) (PubMed).
: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, (2015) (PubMed).
: "ALG-2-interacting Tubby-like protein superfamily member PLSCR3 is secreted by exosomal pathway and taken up by recipient cultured cells." in: Bioscience reports, (2013) (PubMed).
: "Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration." in: The Journal of investigative dermatology, Vol. 132, Issue 12, pp. 2828-37, (2012) (PubMed).
Aliases for ALIX 抗体
ALG-2 interacting protein X (alxA) 抗体programmed cell death 6 interacting protein (PDCD6IP) 抗体
programmed cell death 6 interacting protein (Pdcd6ip) 抗体
ALG-2 interacting protein X (ALiX) 抗体
programmed cell death 6-interacting protein (LOC412662) 抗体
programmed cell death 6 interacting protein (pdcd6ip) 抗体
Programmed cell death 6 interacting protein (Bm1_48390) 抗体
programmed cell death 6 interacting protein L homeolog (pdcd6ip.L) 抗体
AI480591 抗体
AIP1 抗体
Aip1 抗体
aip1 抗体
ALIX 抗体
Alix 抗体
alix 抗体
AW544830 抗体
C76364 抗体
CG12876 抗体
DAIP1 抗体
DDBDRAFT_0167145 抗体
DDBDRAFT_0185177 抗体
DDB_0167145 抗体
DDB_0185177 抗体
Dmel\\CG12876 抗体
DRIP4 抗体
drip4 抗体
Eig2 抗体
GB11744 抗体
HP95 抗体
hp95 抗体
mKIAA1375 抗体
PDCD6IP 抗体
RGD1561176 抗体
wu:fb70d03 抗体
wu:fy65h02 抗体
zgc:63638 抗体
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