AKR1C3 蛋白
(Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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10 results
AKR1C3
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90% by SDS-PAGE
SDS, EAA
Active
1 image
AKR1C3
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % by SDS - PAGE
SDS
1 image
custom-made
AKR1C3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
AKR1C3
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for AKR1C3 蛋白
aldo-keto reductase family 1, member C3 L homeolog (akr1c3.L) 蛋白aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR1C3) 蛋白
aldo-keto reductase family 1 member C2 (LOC722496) 蛋白
aldo-keto reductase family 1 member C3 (AKR1C3) 蛋白
aldo-keto reductase family 1, member C3 (Akr1c3) 蛋白
AKR1C3 蛋白
Akr1c18 蛋白
DD3 蛋白
DDX 蛋白
HA1753 蛋白
HAKRB 蛋白
HAKRe 蛋白
hluPGFS 蛋白
HSD17B5 蛋白
MGC134333 蛋白
PGFS 蛋白
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