The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. [provided by RefSeq, Jul 2008].
Lefevre, Duquenne, Rousseau-Merck, Rogier, Finaz: "Cloning and characterization of SOB1, a new testis-specific cDNA encoding a human sperm protein probably involved in oocyte recognition." in: Biochemical and biophysical research communications, Vol. 259, Issue 1, pp. 60-6, (1999) (PubMed).
Aliases for AKAP3 抗体
A-kinase anchoring protein 3 (AKAP3) 抗体 A kinase (PRKA) anchor protein 3 (Akap3) 抗体 A-kinase anchoring protein 3 (Akap3) 抗体 AKAP3 抗体 AKAP 110 抗体 AKAP110 抗体 CT82 抗体 FSP95 抗体 PRKA3 抗体 Prka3 抗体 SOB1 抗体