This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012].
Eggers, Schafer, Goldenring, Taylor: "D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32869-80, (2009) (PubMed).
Burns-Hamuro, Barraclough, Taylor: "Identification and functional analysis of dual-specific A kinase-anchoring protein-2." in: Methods in enzymology, Vol. 390, pp. 354-74, (2004) (PubMed).
Aliases for AKAP10 抗体
A-kinase anchoring protein 10 (AKAP10) 抗体 A-kinase anchoring protein 10 L homeolog (akap10.L) 抗体 A-kinase anchoring protein 10 (akap10) 抗体 A kinase (PRKA) anchor protein 10 (akap10) 抗体 A kinase (PRKA) anchor protein 10 (Akap10) 抗体 A-kinase anchoring protein 10 (Akap10) 抗体 1500031L16Rik 抗体 AKAP-10 抗体 AKAP10 抗体 Akap10 抗体 B130049N18Rik 抗体 D-AKAP-2 抗体 D-AKAP2 抗体 D-akap2 抗体 fc10g11 抗体 MGC84612 抗体 PRKA10 抗体 si:dkey-197m14.4 抗体 wu:fc10g11 抗体