ShK
产品编号 ABIN1540127
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for ShK (ABIN1540127)
抗原
Toxin ShK (Stoichactishelianthus potassium-channel reduced)
应用范围
Blocking Reagent (BR)
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原理
- ShK is a Kv1.3 channel selective blocker
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序列
- Arg-Ser-Cys3-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys12-Thr-Ala-Phe-Gln-Cys17-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys28-Arg-Lys-Thr-Cys32-Gly-Thr-Cys35-OHDisulfid e bonds between Cys3-Cys35, Cys12-Cys28 and Cys17-Cys32
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限制
- 仅限研究用
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- Toxin ShK (Stoichactishelianthus potassium-channel reduced)
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背景
- ShK has been isolated from the venom of the Carribean seaanemone Stoichactis helianthus. This toxin inhibits voltagedependentpotassium channels. It blocks Kv1.3 (KCNA3)potently and also Kv1.1 (KCNA1), Kv1.4 (KCNA4), and Kv1.6(KCNA6) respectively with 11 pM,16 pM and 165 pM.
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分子量
- 4054.85 Da
抗原
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