Sulindac Sulfone
产品编号 ABIN1027865
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Sulindac Sulfone (ABIN1027865)
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原理
- Sulindac metabolite
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产品特性
- Modulates beta-catenin-mediated effects.
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纯度
- >98 %
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Chemical Name
- {(1Z)-5-Fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}acetic acid
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Formula
- C20H17FO4S
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Solubility
- Soluble to 25 mM in DMSO, 3 mM in ethanol
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说明
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Source: Synthetic.
Appearance: Yellow solid -
限制
- 仅限研究用
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状态
- Solid
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注意事项
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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注意事项
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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储存条件
- -20 °C
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背景
- Sulindac is a nonsteroidal anti-inflammatory drug that is known to prevent recurrence and reduce colorectal polyps. It is a prodrug that is metabolized to a sulfide and sulfone derivative in vivo. The mechanism of action of both is the selective induction of apoptosis. The anti-inflammatory properties of sulindac are mediated by COX inhibition.
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分子量
- 372.41
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CAS-编号
- 59864-04-9
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