Etoposide
产品编号 ABIN1027829
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Etoposide (ABIN1027829)
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原理
- Topoisomerase II inhibitor
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产品特性
- Topoisomerase II inhibitor.
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纯度
- >98 %
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Chemical Name
- (5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-β-D-glucopyranoside
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Formula
- C29H32O13
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Solubility
- Soluble to 100 mM in DMSO
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说明
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Source: Synthetic.
Appearance: White solid -
限制
- 仅限研究用
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状态
- Solid
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注意事项
- Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S53 - Avoid exposure - obtain special instruction before use Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R45 - May cause cancer R62 - Possible risk of impaired fertility R68 - Possible risk of irreversible effects Hazard Phrases: H302-H350 Precautionary Phrases: P201-P308 + P313
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注意事项
- Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S53 - Avoid exposure - obtain special instruction before use Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R45 - May cause cancer R62 - Possible risk of impaired fertility R68 - Possible risk of irreversible effects Hazard Phrases: H302-H350 Precautionary Phrases: P201-P308 + P313
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储存条件
- -20 °C
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背景
- Etoposide inhibits the enzyme topoisomerase II, which unwinds DNA, and be doing so causes the DNA strand to break. Cancer cells are then less likely to be able to repair this damage.
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分子量
- 588.56
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CAS-编号
- 33419-42-0
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