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Fumonisin B1

产品编号 ABIN1027813
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Fumonisin B1 (ABIN1027813)

  • 原理

    Ceramide synthase inhibitor

    产品特性

    Blocks sphingolipid biosynthesis.

    纯度

    >98 %

    Chemical Name

    2,2'-{(19-Amino-11,16,18-trihydroxy-5,9-dimethyl-6,7-icosanediyl)bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid

    Formula

    C34H59NO15

    Solubility

    Soluble to 10 mM in DMSO
  • 说明

    Source: Synthetic.
    Appearance: Beige Solid

    限制

    仅限研究用
  • 状态

    Solid

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281

    储存条件

    -20 °C
  • 背景

    Fumonisin B1 is the most prevalent member of a family of toxins. It is hepatotoxic and nephrotoxic in all animal species. It occupies the space and electrostatic interactions of both sphinganine and fatty acyl-CoA. Due to this mechanism of action, it has toxic effects in humans such as neural tube defects, esophageal cancer, acute mycotoxicosis, and various other carcinogenic effects. Another effect of exposure to FB1 is apoptosis.

    分子量

    721.83

    CAS-编号

    116355-83-0
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