The specific function of this gene has not yet been determined\; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013].
Latest Publications for our ARP3 Actin-Related Protein 3 抗体
Ichikawa, Kanda, Kosugi, Kawachi, Sasaki, Wakai, Kondo: "Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer." in: Journal of proteome research, Vol. 12, Issue 8, pp. 3780-91, (2013) (PubMed).