ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008].
ACVR1C
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
activin A receptor type 1C (ACVR1C) 蛋白 activin A receptor, type IC (Acvr1c) 蛋白 activin A receptor type 1C (Acvr1c) 蛋白 ACVRLK7 蛋白 Alk-7 蛋白 ALK7 蛋白 Alk7 蛋白 C230097P10 蛋白 habrec1 蛋白