Activated Protein C 产品
(Activated Protein C)
Categories
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
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Recommended Activated Protein C 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
Cat. No.
ABIN2195387
Quantity
100 μg
Datasheet
Datasheet
Recommended Activated Protein C ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6953413
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6953414
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963025
Quantity
96 tests
Datasheet
Datasheet
Recommended Activated Protein C 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423603
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7425116
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421329
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Activated Protein C Products
: "A multicenter prospective validation study on disseminated intravascular coagulation in trauma-induced coagulopathy." in: Journal of thrombosis and haemostasis : JTH, Vol. 18, Issue 9, pp. 2232-2244, (2020) (PubMed).: "Activated protein C does not increase in the early phase of trauma with disseminated intravascular coagulation: comparison with acute coagulopathy of trauma-shock." in: Journal of intensive care, Vol. 4, pp. 1, (2016) (PubMed).
: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." in: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).
: "Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model." in: Neuroscience, Vol. 299, pp. 18-27, (2015) (PubMed).
: "Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation." in: Critical care, Vol. 18, Issue 5, pp. 543, (2014) (PubMed).
: "Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study." in: Critical care, Vol. 15, Issue 6, pp. R272, (2013) (PubMed).
: "Intraovarian thrombin and activated protein C signaling system regulates steroidogenesis during the periovulatory period." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 331-40, (2012) (PubMed).
: "High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective ..." in: Scandinavian journal of trauma, resuscitation and emergency medicine, Vol. 20, pp. 27, (2012) (PubMed).
: "Activated protein C attenuates systemic lupus erythematosus and lupus nephritis in MRL-Fas(lpr) mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 6, pp. 3413-21, (2011) (PubMed).
Synonyms and alternative names related to Activated Protein C
APC, WNT signaling pathway regulator (APC), APC, WNT signaling pathway regulator (Apc), adenomatosis polyposis coli (Apc), AI047805, AU020952, AW124434, BTPS2, CC1, DP2, DP2.5, DP3, GS, mAPC, Min, PPP1R46, RATAPCProtein level used designations for Activated Protein C
- adenomatosis polyposis coli tumor suppressor
- adenomatous polyposis coli protein
- deleted in polyposis 2.5
- protein phosphatase 1, regulatory subunit 46
- adenomatosis polyposis coli
- multiple intestinal neoplasia
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