The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008].
Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: "Hepatic metabolite profiles in mice with a suboptimal selenium status." in: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).
Tucci, Herebian, Sturm, Seibt, Spiekerkoetter: "Tissue-specific strategies of the very-long chain acyl-CoA dehydrogenase-deficient (VLCAD-/-) mouse to compensate a defective fatty acid ?-oxidation." in: PLoS ONE, Vol. 7, Issue 9, pp. e45429, (2012) (PubMed).
Mells, Fu, Sharma, Olson, Cheng, Handy, Saxena, Sorescu, Anania: "Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 2, pp. G225-35, (2012) (PubMed).
Aliases for ACADL 抗体
acyl-CoA dehydrogenase long chain (acadl) 抗体 acyl-CoA dehydrogenase long chain (ACADL) 抗体 acyl-CoA dehydrogenase, long chain (acadl) 抗体 acyl-CoA dehydrogenase, long chain (Acadl) 抗体 acyl-CoA dehydrogenase, long chain L homeolog (acadl.L) 抗体 acyl-CoA dehydrogenase, long chain (ACADL) 抗体 acyl-Coenzyme A dehydrogenase, long-chain (Acadl) 抗体 AA960361 抗体 ACAD4 抗体 ACOADA 抗体 AU018452 抗体 C79855 抗体 LCAD 抗体 zgc:55656 抗体