anti-tRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae) (THG1L) 抗体

Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. 再加上,我们可以发THG1L 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
THG1L 54974 Q9NWX6
THG1L 66628 Q9CY52
THG1L 303067 Q5M965
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Showing 10 out of 18 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-THG1L Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Spleen 100 μL 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-Thg1l Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Spleen 100 μL 2至3个工作日
Bat 非结合性 WB 100 μL 11至14个工作日
非结合性 WB 100 μL 11至14个工作日
非结合性 WB THG1L antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日
非结合性 WB   100 μL 2至3个工作日
小鼠 非结合性 ELISA, WB Western Blot analysis of THG1L expression in transfected 293T cell line by THG1L monoclonal antibody (M01), clone 4F11.Lane 1: THG1L transfected lysate (Predicted MW: 34.8 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged THG1L is 1 ng/ml as a capture antibody. 100 μg 11至12个工作日
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (55.33 KDa) . 50 μL 11至12个工作日
小鼠 非结合性 WB Western Blot analysis of THG1L expression in transfected 293T cell line by THG1L MaxPab polyclonal antibody.Lane1:ICF45 transfected lysate(32.78 KDa).Lane2:Non-transfected lysate. THG1L MaxPab polyclonal antibody. Western Blot analysis of THG1L expression in A-431. 50 μg 11至12个工作日
非结合性 WB   50 μg 4至8个工作日


Human tRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae) (THG1L) interaction partners

  1. Study proposes that homozygosity for the p.Val55Ala mutation in tRNA-histidine guanylyltransferase 1 like (THG1L) is the cause of the abnormal mitochondrial network in the patient fibroblasts, likely by interfering with THG1L activity towards MFN2.

  2. The high-resolution crystal structure of human Thg1 reveals remarkable structural similarity between canonical DNA/RNA polymerases and eukaryotic Thg1.

  3. IHG-1 is a novel regulator of both mitochondrial dynamics and bioenergetic function and contributes to cell survival following oxidant stress. Increased IHG-1 expression may contribute to pathogenesis of diabetic kidney disease.

  4. IHG-1 increases mitochondrial biogenesis by promoting PGC-1alpha-dependent processes, potentially contributing to the pathogenesis of renal fibrosis

  5. The catalytic domain of Thg1 shares both a common architecture and a two-metal ion-dependent mechanism with canonical 5'-3' DNA polymerases.

  6. ICF45 is a highly conserved novel protein, which is expressed in a cell cycle-dependent manner and seemed to be involved in cell cycle progression and cell proliferation

  7. induced in high glucose-1 (IHG-1)which increases in diabetic nephropathy, may enhance the actions of TGF-beta1 and contribute to the development of tubulointerstitial fibrosis

THG1L 抗原简介


Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis (By similarity).

Gene names and symbols associated with THG1L

  • tRNA-histidine guanylyltransferase 1 like (THG1L) 抗体
  • tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) (Thg1l) 抗体
  • tRNA-histidine guanylyltransferase 1-like (Thg1l) 抗体
  • 1700121M19Rik 抗体
  • 5730409G07Rik 抗体
  • AA387658 抗体
  • ICF45 抗体
  • IHG-1 抗体

Protein level used designations for THG1L

probable tRNA(His) guanylyltransferase , tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) , interphase cytoplasmic foci protein 45 , probable tRNA(His) guanylyltransferase-like , induced by high glucose-1 , nterphase cyctoplasmic foci protein 45

416242 Gallus gallus
462226 Pan troglodytes
479315 Canis lupus familiaris
715853 Macaca mulatta
54974 Homo sapiens
66628 Mus musculus
303067 Rattus norvegicus
507084 Bos taurus
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