This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
Latest Publications for our rho Family GTPase 3 蛋白
Breslin, Daines, Doggett, Kurtz, Souza-Smith, Zhang, Wu, Yuan: "Rnd3 as a Novel Target to Ameliorate Microvascular Leakage." in: Journal of the American Heart Association, Vol. 5, Issue 4, pp. e003336, (2016) (PubMed).