gamma Glutamyltransferase 1 蛋白 (GGT1)

The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. 再加上,我们可以发gamma Glutamyltransferase 1 抗体 (159)gamma Glutamyltransferase 1 试剂盒 (61)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GGT1 2678 P19440
GGT1 14598 Q60928
GGT1 116568 P07314
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$5,355.45
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Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50至55个工作日
$7,626.01
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人细胞 大鼠 His tag 100 μg Log in to see 20至21个工作日
$437.80
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至18个工作日
$672.00
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 20 Days
$5,465.26
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酵母菌 Schizosaccharomyces pombe His tag   1 mg Log in to see 60至71个工作日
$2,016.67
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$3,041.50
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小麦胚 非结合性   10 μg Log in to see 11至12个工作日
$654.29
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大肠杆菌(E. Coli) His tag   100 μg Log in to see 15至18个工作日
$560.00
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GGT1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine) ,
, ,
Rat (Rattus) ,

更多gamma Glutamyltransferase 1 (GGT1)互动伙伴

Human gamma Glutamyltransferase 1 (GGT1) interaction partners

  1. Data suggest that increased serum GGT level is independently associated with prevalence of hyperuricemia in middle-aged and elderly Chinese females.

  2. elevated preoperative serum gamma-GGT was significantly associated with advanced tumor stage and aggressive tumor behaviors, and serum gamma-GGT can be considered as a prognostic factor for hepatocellular carcinoma patients after liver transplantation

  3. Higher pre-treatment GGT serum levels were independently associated with unfavorable prognosis in women withu terine leiomyosarcoma (ULMS). Thus, GGT seems to be a useful novel biomarker in ULMS.

  4. In a large Korean population-based study, elevated GGT levels were significantly associated with increased risk of atrial fibrillation.

  5. The probe exhibits very high selectivity and sensitivity toward GGT activity from in vitro to in vivo and in clinical samples, which offers a promising tool for investigations of the GGT-overexpressing related biological process including tumor diagnosis and prognosis in living organisms.

  6. both tumor GGT and serum GGT are poor prognostic factors in gastric cancer

  7. The GPR could be used as a non-invasive marker to predict liver fibrosis and cirrhosis in CHB-NAFLD individuals.

  8. This study demonstrated a positive association between serum GGT levels and LV diastolic dysfunction and LV hypertrophy in a large cohort of middle-aged men and women independent of potential confounders.

  9. we found that serum exosomal GGT activity was significantly higher in prostate cancer (PC), patients than in benign prostatic hyperplasia (BPH) patients. In support of this finding, immunohistochemical analysis showed increased GGT1 expression in PC tissues compared with BPH tissues. Our results suggest that serum exosomal GGT activity could be a useful biomarker for PC

  10. GGT activity may serve as a potential surrogate biomarker of atherogenic risk and metabolic health status

Mouse (Murine) gamma Glutamyltransferase 1 (GGT1) interaction partners

  1. These findings elucidate a novel mechanism of inflammation-associated osteoclastogenesis, which involves TLR4 (显示 TLR4 蛋白) recognition of gamma-glutamyltranspeptidase and subsequent activation of MyD88 (显示 MYD88 蛋白)-dependent signaling.

  2. the present study developed a liver-specific GGT-overexpressing mice model and found that GGT elevation in short term had no effects on glucose metabolism but could increase insulin (显示 INS 蛋白) sensitivity through enhancing the activity of insulin (显示 INS 蛋白) signaling pathway.

  3. Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE (显示 APOE 蛋白)-knockout mice.

  4. Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.

  5. Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.

  6. Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.

  7. prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase (显示 TYR 蛋白) in pigment cells.

  8. GGT regulates osteoclast biology at least partly independently of sex steroids

  9. GGT stimulates RANKL (显示 TNFSF11 蛋白) expression

  10. GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.

蛋白简介gamma Glutamyltransferase 1 (GGT1)

蛋白简介

The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with GGT1

  • gamma-glutamyltransferase 1a (ggt1a)
  • gamma-glutamyltransferase 1 (GGT1)
  • gamma-glutamyltransferase 1 (Ggt1)
  • gamma-glutamyltransferase 1 (ggt1)
  • gamma-glutamyltranspeptidase 1 (LOC470168)
  • gamma-glutamyltransferase 1 L homeolog (ggt1.L)
  • gamma-glutamyltransferase 1 (ggt)
  • gamma-glutamyltransferase 1 (Bcep18194_A6223)
  • gamma-glutamyltransferase (ggt)
  • gamma-glutamyltransferase 1 (h16_A1098)
  • gamma-glutamyltransferase 1 (Shewana3_2487)
  • gamma-glutamyltransferase 1 (Bcep1808_2978)
  • gamma-glutamyltranspeptidase Ggt1 (ggt1)
  • cd224 蛋白
  • D22S672 蛋白
  • D22S732 蛋白
  • dwg 蛋白
  • GGLUT 蛋白
  • ggt 蛋白
  • GGT-1 蛋白
  • GGT 1 蛋白
  • GGT1 蛋白
  • ggt1-a 蛋白
  • GGT2 蛋白
  • Ggtp 蛋白
  • gtg 蛋白
  • zgc:64172 蛋白

Protein level used designations for GGT1

gamma-glutamyltransferase 1 , gamma-glutamyltranspeptidase 1 , GGT 1 , gamma-glutamyl transpeptidase , glutathione hydrolase 1 , leukotriene-C4 hydrolase , glutamyl transpeptidase , gamma glutamyl-transferase 1 , gamma-glutamyltransferase 2 , ggt 1 , gamma-glutamyltransferase 1 a , Gamma-glutamyltranspeptidase 1 , gamma-glutamyltranspeptidase 1-like , Gamma-glutamyltransferase 1

GENE ID SPECIES
393387 Danio rerio
397095 Sus scrofa
2678 Homo sapiens
14598 Mus musculus
116568 Rattus norvegicus
416945 Gallus gallus
448376 Xenopus (Silurana) tropicalis
470168 Pan troglodytes
486400 Canis lupus familiaris
615582 Bos taurus
707545 Macaca mulatta
734898 Xenopus laevis
3514074 Psychrobacter arcticus 273-4
3721873 Rhodobacter sphaeroides 2.4.1
3751456 Burkholderia sp. 383
4005058 Burkholderia xenovorans LB400
4248665 Ralstonia eutropha H16
4476668 Shewanella sp. ANA-3
4954724 Burkholderia vietnamiensis G4
100050188 Equus caballus
100195220 Salmo salar
100386116 Callithrix jacchus
100477414 Ailuropoda melanoleuca
100554005 Anolis carolinensis
100717316 Cavia porcellus
2543536 Schizosaccharomyces pombe 972h-
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