gamma Glutamyltransferase 1 蛋白 (GGT1)

The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. 再加上,我们可以发gamma Glutamyltransferase 1 抗体 (164)gamma Glutamyltransferase 1 试剂盒 (62)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GGT1 2678 P19440
GGT1 14598 Q60928
GGT1 116568 P07314
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50至55个工作日
人细胞 大鼠 His tag 100 μg Log in to see 14至16个工作日
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至18个工作日
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 20 Days
酵母菌 Schizosaccharomyces pombe His tag   1 mg Log in to see 60至71个工作日
酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
小麦胚 非结合性   10 μg Log in to see 11至12个工作日
大肠杆菌(E. Coli) His tag   100 μg Log in to see 15至18个工作日

GGT1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine) ,
, ,
Rat (Rattus) ,

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Human gamma Glutamyltransferase 1 (GGT1) interaction partners

  1. Overall, the findings cannot confirm a strong causal effect of gamma-glutamyltransferase on Alzheimer's disease risk.

  2. Whole-genome sequencing revealed the presence of a 16.9 kb homozygous deletion in GGT1, one of the genes encoding enzymes with gamma-glutamyl transpeptidase activity in the human genome

  3. Serum gamma-Glutamyltransferase was associated with the risk of acute coronary syndrome in Chinese patients.

  4. Both GGT and ALT are effective markers for identifying Metabolically Unhealthy Obese.

  5. no association of rs4820599 with polycystic ovary syndrome

  6. gamma glutamyl transferase 1 (GGT1), the key enzyme of the gamma-glutamyl cycle, is expressed at approximately 100-fold lower levels in ChRCC compared with normal kidney, while no change in GGT1 expression was found in clear cell RCC (ccRCC).

  7. Data suggest that increased serum GGT level is independently associated with prevalence of hyperuricemia in middle-aged and elderly Chinese females.

  8. elevated preoperative serum gamma-GGT was significantly associated with advanced tumor stage and aggressive tumor behaviors, and serum gamma-GGT can be considered as a prognostic factor for hepatocellular carcinoma patients after liver transplantation

  9. Higher pre-treatment GGT serum levels were independently associated with unfavorable prognosis in women withu terine leiomyosarcoma (ULMS). Thus, GGT seems to be a useful novel biomarker in ULMS.

  10. In a large Korean population-based study, elevated GGT levels were significantly associated with increased risk of atrial fibrillation.

  11. The probe exhibits very high selectivity and sensitivity toward GGT activity from in vitro to in vivo and in clinical samples, which offers a promising tool for investigations of the GGT-overexpressing related biological process including tumor diagnosis and prognosis in living organisms.

  12. both tumor GGT and serum GGT are poor prognostic factors in gastric cancer

  13. The GPR could be used as a non-invasive marker to predict liver fibrosis and cirrhosis in CHB-NAFLD individuals.

  14. This study demonstrated a positive association between serum GGT levels and LV diastolic dysfunction and LV hypertrophy in a large cohort of middle-aged men and women independent of potential confounders.

  15. we found that serum exosomal GGT activity was significantly higher in prostate cancer (PC), patients than in benign prostatic hyperplasia (BPH) patients. In support of this finding, immunohistochemical analysis showed increased GGT1 expression in PC tissues compared with BPH tissues. Our results suggest that serum exosomal GGT activity could be a useful biomarker for PC

  16. GGT activity may serve as a potential surrogate biomarker of atherogenic risk and metabolic health status

  17. High initial GGT concentration and increases in GGT concentration over time should be considered independent predictors of and to have a combined effect on incident metabolic syndrome.

  18. gamma-glutamyltransferase may have a role in nasopharyngeal carcinoma

  19. Formation of LTD4 was rapid when catalyzed by gamma-glutamyl transpeptidase (GGT)1 in the A549 epithelial lung cancer cell line, but considerably slower when catalyzed by GGT5 in primary bronchial epithelial cells. When A549 cells were cultured in the presence of IL-1beta, GGT1 expression increased about 2-fold. Also exosomes from A549 cells contained GGT1 and augmented LTD4 formation.

  20. Results show a weak genetic evidence that GGT levels may have a causal role in the development of type 2 diabetes.

Mouse (Murine) gamma Glutamyltransferase 1 (GGT1) interaction partners

  1. GGsTop is a newly-discovered gamma-glutamyl transpeptidase (GGT) inhibitor...GGsTop treated Oral mucositis (OM) quickly and safely. GGsTop is highly valuable for use as a treatment for OM

  2. These findings elucidate a novel mechanism of inflammation-associated osteoclastogenesis, which involves TLR4 recognition of gamma-glutamyltranspeptidase and subsequent activation of MyD88-dependent signaling.

  3. the present study developed a liver-specific GGT-overexpressing mice model and found that GGT elevation in short term had no effects on glucose metabolism but could increase insulin sensitivity through enhancing the activity of insulin signaling pathway.

  4. Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE-knockout mice.

  5. Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.

  6. Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.

  7. Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.

  8. Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia

  9. prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase in pigment cells.

  10. GGT regulates osteoclast biology at least partly independently of sex steroids

  11. GGT stimulates RANKL expression

  12. GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.

蛋白简介gamma Glutamyltransferase 1 (GGT1)


The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with GGT1

  • gamma-glutamyltransferase 1a (ggt1a)
  • gamma-glutamyltransferase 1 (GGT1)
  • gamma-glutamyltransferase 1 (Ggt1)
  • gamma-glutamyltransferase 1 (ggt1)
  • gamma-glutamyltranspeptidase 1 (LOC470168)
  • gamma-glutamyltransferase 1 L homeolog (ggt1.L)
  • gamma-glutamyltransferase 1 (ggt)
  • gamma-glutamyltransferase 1 (Bcep18194_A6223)
  • gamma-glutamyltransferase (ggt)
  • gamma-glutamyltransferase 1 (h16_A1098)
  • gamma-glutamyltransferase 1 (Shewana3_2487)
  • gamma-glutamyltransferase 1 (Bcep1808_2978)
  • gamma-glutamyltranspeptidase Ggt1 (ggt1)
  • cd224 蛋白
  • D22S672 蛋白
  • D22S732 蛋白
  • dwg 蛋白
  • GGLUT 蛋白
  • ggt 蛋白
  • GGT-1 蛋白
  • GGT1 蛋白
  • GGT 1 蛋白
  • ggt1-a 蛋白
  • GGT2 蛋白
  • Ggtp 蛋白
  • gtg 蛋白
  • zgc:64172 蛋白

Protein level used designations for GGT1

gamma-glutamyltransferase 1 , gamma-glutamyltranspeptidase 1 , GGT 1 , gamma-glutamyl transpeptidase , glutathione hydrolase 1 , leukotriene-C4 hydrolase , glutamyl transpeptidase , gamma glutamyl-transferase 1 , gamma-glutamyltransferase 2 , ggt 1 , gamma-glutamyltransferase 1 a , Gamma-glutamyltranspeptidase 1 , gamma-glutamyltranspeptidase 1-like , Gamma-glutamyltransferase 1

393387 Danio rerio
397095 Sus scrofa
2678 Homo sapiens
14598 Mus musculus
116568 Rattus norvegicus
416945 Gallus gallus
448376 Xenopus (Silurana) tropicalis
470168 Pan troglodytes
486400 Canis lupus familiaris
615582 Bos taurus
707545 Macaca mulatta
734898 Xenopus laevis
3514074 Psychrobacter arcticus 273-4
3721873 Rhodobacter sphaeroides 2.4.1
3751456 Burkholderia sp. 383
4005058 Burkholderia xenovorans LB400
4248665 Ralstonia eutropha H16
4476668 Shewanella sp. ANA-3
4954724 Burkholderia vietnamiensis G4
100050188 Equus caballus
100195220 Salmo salar
100386116 Callithrix jacchus
100477414 Ailuropoda melanoleuca
100554005 Anolis carolinensis
100717316 Cavia porcellus
2543536 Schizosaccharomyces pombe 972h-
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