anti-alpha Hemoglobin Stabilizing Protein (aHSP) 抗体

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. 再加上,我们可以发aHSP 试剂盒 (26)aHSP 蛋白 (16)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
aHSP 51327 Q9NZD4
aHSP 170812 Q9CY02
aHSP 293522  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单
  • orders@antibodies-online.cn

antibodies-online.cn销售最多的anti-aHSP 抗体

Showing 10 out of 52 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 FM, IHC (fp), ELISA, WB 100 μL Log in to see 5至7个工作日
$583.50
详细
大鼠 非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Rat Liver Tissue; Lane2: Mouse Liver Tissue. 100 μg Log in to see 13至16个工作日
$342.00
详细
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: ERAF Antibody [NBP1-84008] - Staining of human bone marrow shows strong cytoplasmic and nuclear positivity in subsets of hematopoietic cells. Western Blot: ERAF Antibody  - Lane 1: Marker  250, 130, 95, 72, 55, 36, 28, 17, 10 Lane 2: Negative control (vector only transfected HEK293T lysate) Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY413883) 0.1 mL Log in to see 10至13个工作日
$491.63
详细
小鼠 非结合性 ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded stomach tissue 100 μg Log in to see 15至18个工作日
$324.00
详细
非结合性 ELISA, IHC, IHC (p), WB 100 μL Log in to see 7至9个工作日
$639.83
详细
非结合性 ICC, IHC, WB Western Blot; Sample: Rat Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Human aHSP Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15至18个工作日
$316.00
详细
非结合性 WB Western blot analysis of AHSP expression in mouse liver (A), rat liver (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
大鼠 非结合性 IF/ICC, IHC, IP, WB Western blot analysis of (1) Rat Liver Tissue and (2) Mouse Liver Tissue. Western blot analysis of recombinant Rat aHSP. 100 μg Log in to see 11至18个工作日
$440.62
详细
小鼠 非结合性 WB Western blot analysis of extracts of various cell lines, using AHSP antibody (ABIN5973863) at 1/1000 dilution. 100 μL Log in to see 11至16个工作日
$426.40
详细
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged ERAF is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.96 KDa) . 100 μg Log in to see 11至12个工作日
$440.00
详细

引用最多的anti-aHSP 抗体

  1. Human Monoclonal aHSP Primary Antibody for ELISA, WB - ABIN526641 : Wang, Fang, Guo, Ren, Zhang: Transgenic human alpha-hemoglobin stabilizing protein could partially relieve betaIVS-2-654-thalassemia syndrome in model mice. in Human gene therapy 2010 (PubMed)

  2. Mouse (Murine) Polyclonal aHSP Primary Antibody for FM, IHC (fp) - ABIN1043695 : Nasimuzzaman, Khandros, Wang, Kong, Zhao, Weiss, Rivella, Weiss, Persons: Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia. in American journal of hematology 2010 (PubMed)

更多抗aHSP的相互作用对抗体

Human alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. In the presence of free alpha subunits and H2O2, both HbA (显示 SCN2A 抗体) and HbE (显示 HBe1 抗体) showed bCys93 oxidation which increased with higher H2O2 concentrations. In the presence of Alpha-hemoglobin stabilizing protein (AHSP)Cys93 oxidation was substantially reduced in both proteins.in the presence of excess free alpha-subunit (显示 POLG 抗体) and under the same oxidative conditions, these events are substantially increased for HbE (显示 HBe1 抗体) compared to HbA (显示 SCN2A 抗体)

  2. Findings indicate that alpha-hemoglobin-stabilizing protein (AHSP) expression is a biomarker of hemoglobin (显示 HBB 抗体) H (HbH (显示 HBA1 抗体)) disease severity and infer an important role of AHSP in modulating the pathophysiology of this disease.

  3. AHSP is predominantly expressed in erythroid precursors in bone marrow biopsy specimens from patients with hematologic malignancies.

  4. AHSP expression was higher in patients with sickle cell anemia versus thalassemia, with no significant difference between BTM and BTI. Expression was higher in patients with NTDT and on hydroxyurea therapy.

  5. In maturing RBC (显示 CACNA1C 抗体) progenitors AHSP bind to free alpha-globin (显示 HBA1 抗体) chains to increase the HbA (显示 SCN2A 抗体) production. (Review)

  6. analysis showed binding of STAT3 (显示 STAT3 抗体) to AHSP promoter and binding was significantly augmented with IL6 (显示 IL6 抗体) stimulation and upon alpha-globin (显示 HBA1 抗体) overexpression

  7. The relationship between AHSP gene expression, disease severity, and the beta/alpha globin (显示 HBA1 抗体) mRNA ratio was studied among different homozygote beta-thalassemia patients.

  8. alpha-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy (显示 GCG 抗体)-alpha-hemoglobin and weakens the iron-oxygen bond.

  9. alpha-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of alpha-subunits of human HbA (显示 SCN2A 抗体) with hydrogen peroxide.

  10. AHSP acts as a molecular chaperone (显示 HSP90AA1 抗体) by rapidly binding and stabilizing met-alpha hemichrome folding intermediates

Mouse (Murine) alpha Hemoglobin Stabilizing Protein (aHSP) interaction partners

  1. role of alpha-hemoglobin stabilizing protein in hemoglobin assembly

  2. Endogenous AHSP is not limiting for alpha-globin (显示 HBA-A1 抗体) detoxification in beta-thalassemic mice.

  3. activin A (显示 INHBA 抗体) does not appear to affect the exocrine or endocrine components of the pancreas, but promotes differentiation of pancreatic tissue into intestine via a Shh (显示 SHH 抗体)-dependent mechanism

  4. Loss of AHSP impairs erythropoiesis and exacerbates beta-thalassemia.

  5. These results support the hypothesis that EKLF (显示 KLF1 抗体) acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin (显示 HBB 抗体) genes and indicate that EKLF (显示 KLF1 抗体) may play similar roles for other erythroid genes.

  6. developmental stage- and differentiation state-specific regulation of the nuclear transport of EKLF (显示 KLF1 抗体) might be one of the steps necessary for the switch-on of the mammalian adult beta globin (显示 HBB 抗体) gene transcription

  7. AHSP also acts as a molecular chaperone to stabilize nascent alpha-globin for hemoglobin A assembly

  8. The expression of AHSP in a subclone of murine erythroleukemia cells in relationship to prion protein (显示 PRNP 抗体) on the cell surface is reported.

aHSP 抗原简介

蛋白简介

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity).

Gene names and symbols associated with aHSP

  • alpha hemoglobin stabilizing protein (AHSP) 抗体
  • alpha hemoglobin stabilizing protein (Ahsp) 抗体
  • alpha-hemoglobin-stabilizing protein-like (LOC100620111) 抗体
  • AHSP 抗体
  • EDRF 抗体
  • Eraf 抗体

Protein level used designations for aHSP

alpha hemoglobin stabilizing protein , erythroid associated factor , alpha hemoglobin stabilising protein , alpha-hemoglobin-stabilizing protein , erythroid differentiation associated factor , erythroid differentiation-related factor , erythroid-associated factor

GENE ID SPECIES
454073 Pan troglodytes
714392 Macaca mulatta
100127218 Ovis aries
100340962 Oryctolagus cuniculus
51327 Homo sapiens
170812 Mus musculus
338381 Bos taurus
293522 Rattus norvegicus
100712877 Cavia porcellus
100620111 Sus scrofa
anti-aHSP (aHSP) 抗体 精选生产商
您还需要查找其他产品吗?