alpha 1, 4-Galactosyltransferase 蛋白 (A4GALT)

The protein encoded by A4GALT catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. 再加上,我们可以发A4GALT 抗体 (69)A4GALT 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
A4GALT 53947 Q9NPC4
A4GALT 63888 Q9JI93
A4GALT 239559 Q67BJ4
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Showing 7 out of 13 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$5,355.45
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) 非结合性 SDS-PAGE analysis of Human a4GALT Protein. 100 μg Log in to see 11至18个工作日
$596.97
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大肠杆菌(E. Coli) 小鼠 非结合性 SDS-PAGE analysis of Mouse a4GALT Protein. 100 μg Log in to see 11至18个工作日
$625.39
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大肠杆菌(E. Coli) 大鼠 非结合性 SDS-PAGE analysis of Rat a4GALT Protein. 100 μg Log in to see 11至18个工作日
$639.61
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酵母菌 Pongo pygmaeus His tag   1 mg Log in to see 60至71个工作日
$2,541.00
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A4GALT 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, , ,
Rat (Rattus)

Mouse (Murine) ,
, ,

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Human alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

  1. A4GALT SNPs spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group (显示 DARC 蛋白) system

  2. Study reports a novel mutation in the A4GALT gene that was responsible for a p phenotype in a Chinese individual.

  3. Mutation in the A4GALT gene is associated with rare p phenotype in P1Pk blood group (显示 DARC 蛋白) system.

  4. The results of this investigation demonstrate a consistent association of A4GALT SNPs rs2143918 and rs5751348 with the P1/P2 phenotypes and suggest that SNP rs5751348 may lead to allelic variations in A4GALT gene expression

  5. these data elucidate a new explanation underlying the p phenotype, implicating the deleted regions of A4GALT as crucial for P1 and P(k) synthesis, possibly due to loss of binding sites for erythroid transcription factors.

  6. P1-decorated PSGL-1 (显示 SELPLG 蛋白)/mIgG2b bound with high avidity to both Stx1 (显示 STX1A 蛋白) and Stx2 (显示 STX2 蛋白), and as such constitutes a potential therapeutic inhibitor of these toxins.

  7. Results suggest that the C631G mutation alters the acceptor specificity of Gb3/CD77 synthase, rendering it able to catalyze synthesis of the Gal (显示 GAL 蛋白)(alpha1-4)Gal (显示 GAL 蛋白) and Gal (显示 GAL 蛋白)(alpha1-4)GalNAc moieties.

  8. Increased globotriaosylceramide levels are detected in a transgenic mouse expressing human alpha1,4-galactosyltransferase (显示 GGTA1 蛋白) in a mouse model for treating Fabry disease.

  9. Data showed that GRINA-C was associated with Gb3 synthase, and may demonstrate a new type of posttranscriptional regulation of glycosyltransferases.

  10. of A4GALT mRNA in cultured human bone marrow cells revealed novel transcripts containing only the noncoding exon 1 and a sequence (here termed exon 2a) from intron 1.

Mouse (Murine) alpha 1, 4-Galactosyltransferase (A4GALT) interaction partners

蛋白简介A4GALT

蛋白简介

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.

Gene names and symbols associated with A4GALT

  • alpha 1,4-galactosyltransferase (P blood group) (A4GALT)
  • alpha 1,4-galactosyltransferase (A4galt)
  • alpha 1,4-galactosyltransferase (A4GALT)
  • alpha 1,4-galactosyltransferase (P blood group) (A4galt)
  • A4GALT1 蛋白
  • A14GALT 蛋白
  • Gb3 蛋白
  • Gb3S 蛋白
  • P(k) 蛋白
  • P1 蛋白
  • P1PK 蛋白
  • PK 蛋白

Protein level used designations for A4GALT

CD77 synthase , GB3 synthase , P blood group (P one antigen) , P(k) antigen synthase , P1/Pk synthase , UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase , alpha-1,4-N-acetylglucosaminyltransferase , alpha4Gal-T1 , globotriaosylceramide synthase , lactosylceramide 4-alpha-galactosyltransferase , Gb3 synthase , alpha-1,4-galactosyltransferase , Gb3/CD77 synthase , alpha 1,4-galactosyltransferase (globotriaosylceramide synthase) , alpha 1,4-galactosyltransferase (globotriaosylceramide synthase, P blood group) , gb3 synthase

GENE ID SPECIES
53947 Homo sapiens
63888 Rattus norvegicus
239559 Mus musculus
418223 Gallus gallus
481222 Canis lupus familiaris
470230 Pan troglodytes
100721247 Cavia porcellus
618369 Bos taurus
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