Zinc Metalloproteinase, Ste24 (Zmpste24) ELISA试剂盒

Zmpste24 encodes a member of the peptidase M48A family. 再加上,我们可以发Zinc Metalloproteinase, Ste24 抗体 (128)Zinc Metalloproteinase, Ste24 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
Zmpste24 10269 O75844
大鼠 Zmpste24 Zmpste24 313564  
Zmpste24 230709 Q80W54
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适于 Zinc Metalloproteinase, Ste24 相互作用对的更多 ELISA 试剂盒

Human Zinc Metalloproteinase, Ste24 (Zmpste24) interaction partners

  1. ZMPSTE24 is a downstream effector of IFITM3 (显示 IFITM3 ELISA试剂盒) and is important for interferon (显示 IFNA ELISA试剂盒)-induced transmembrane antiviral activity.

  2. ZMPSTE24 is an important element for innate host defense against a broad spectrum of pathogenic viruses.

  3. This case demonstrates that accumulation of prelamin A, independent of the loss of function of ZMPSTE24 metallopeptidase (显示 ECEL1 ELISA试剂盒) that catalyzes processing of prelamin A, can cause a progeroid disorder and that a cell biology assay could be used in precision medicine to identify a potential therapy.

  4. used a fluorogenic assay of the activity of purified ZMPSTE24 to demonstrate that HIV protease inhibitors directly inhibit the human enzyme in a manner indicative of a competitive mechanism

  5. the present study suggests that inhibition of ZMPSTE24 by both mutational and expressional pathways might together play a role in tumorigenesis of colorectal cancer and gastric cancer harboring microsatellite instability phenotype.

  6. results establish that the substrate profile of Ste24p is broader than anticipated, being more similar to that of the M16A protease family than that of the Rce1p CAAX protease with which it has been functionally associated

  7. ZMPSTE24 downregulation is a major contributor in VSMC dysfunctions resulting from LMNA (显示 LMNA ELISA试剂盒) mutations or PI treatments that could translate in early atherosclerosis at the clinical level.

  8. Here, we report on a familial c.50delA (p.Lys17Serfs*21) mutation of the ZMPSTE24 gene, causing RD in two siblings.

  9. complete loss-of-function of ZMPSTE24 leads to RD, whereas other less severe phenotypes are associated with at least one haploinsufficient allele.

  10. miR (显示 MLXIP ELISA试剂盒)-141-3p, which is overexpressed during senescence as a result of epigenetic regulation, is able to decrease ZMPSTE24 expression levels, and leads to an upregulation of prelamin A in human mesenchymal stem cells.

Mouse (Murine) Zinc Metalloproteinase, Ste24 (Zmpste24) interaction partners

  1. these findings suggest that downregulated miR3425p is involved in regulating cell proliferation and cell cycles in Zmpste24/ MEFs by suppressing GAS2 in vitro.

  2. ZMPSTE24 is a downstream effector of IFITM3 (显示 IFITM3 ELISA试剂盒) and is important for interferon (显示 IFNA ELISA试剂盒)-induced transmembrane antiviral activity.

  3. ZMPSTE24 is an important element for innate host defense against a broad spectrum of pathogenic viruses.

  4. we identified the abnormal lamin A (显示 LMNA ELISA试剂盒) (prelamin A), accompanied by a down-regulation of a lamin A (显示 LMNA ELISA试剂盒) processing enzyme (Zmpste24) in the kidney of the GMF (显示 GMFB ELISA试剂盒) transgenic mice

  5. In Zmpste24(-/-) mice, histone H4 was hypoacetylated at a lysine 16 residue (H4K16), and this defect was attributed to the reduced association of a histone acetyltransferase (显示 HAT ELISA试剂盒), Mof (显示 KAT8 ELISA试剂盒), to the nuclear matrix.

  6. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

  7. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

  8. Zmpste24 has a role in processing of prelamin A and lack of Zmpste24 results in a brittle bone phenotype

  9. the progeria-like phenotypes caused by the lack of Zmpste24 in knockout mice is eliminated by heterozygosity for Lmna (显示 LMNA ELISA试剂盒)

  10. Lack of functional Zmpste24, a metalloproteinase responsible for the maturation of prelamin A, also results in progeroid phenotypes in mice

Zinc Metalloproteinase, Ste24 (Zmpste24) 抗原简介

Antigen Summary

This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.

Gene names and symbols associated with Zmpste24

  • zinc metallopeptidase STE24 (ZMPSTE24) 抗体
  • zinc metallopeptidase STE24 L homeolog (zmpste24.L) 抗体
  • zinc metallopeptidase STE24 (zmpste24) 抗体
  • CAAX prenyl protease (zmpste24) 抗体
  • Peptidase family M48 family protein (ATSTE24) 抗体
  • zinc metallopeptidase STE24 (Zmpste24) 抗体
  • zinc metallopeptidase, STE24 (Zmpste24) 抗体
  • zinc metallopeptidase, STE24 homolog (zmpste24) 抗体
  • A530043O15Rik 抗体
  • D030046F19 抗体
  • DDBDRAFT_0189115 抗体
  • DDBDRAFT_0237846 抗体
  • DDB_0189115 抗体
  • DDB_0237846 抗体
  • F2N1.21 抗体
  • F2N1_21 抗体
  • Face-1 抗体
  • FACE1 抗体
  • fi45a02 抗体
  • HGPS 抗体
  • MADB 抗体
  • PRO1 抗体
  • STE24 抗体
  • Ste24p 抗体
  • wu:fi45a02 抗体
  • zgc:55655 抗体

Protein level used designations for Zmpste24

zinc metallopeptidase (STE24 homolog, S. cerevisiae) , zinc metallopeptidase (STE24 homolog) , zinc metallopeptidase STE24 homolog , zinc metalloproteinase STE24 homolog , CAAX prenyl protease 1 homolog , STE24 endopeptidase , zinc metalloproteinase , zinc metallopeptidase STE24 , CAAX prenyl protease 1 homolog-like , farnesylated proteins-converting enzyme 1 , prenyl protein-specific endoprotease 1 , zinc metalloproteinase Ste24 homolog , zinc metallopeptidase, STE24 homolog , zinc metalloproteinase, STE24 homolog , farnesylated-proteins converting enzyme 1 , zinc metalloproteinase (STE24 homolog, yeast)

GENE ID SPECIES
419572 Gallus gallus
447784 Xenopus laevis
456790 Pan troglodytes
482460 Canis lupus familiaris
550009 Xenopus (Silurana) tropicalis
693765 Macaca mulatta
8627861 Dictyostelium discoideum AX4
100032108 Monodelphis domestica
100339077 Oryctolagus cuniculus
100404786 Callithrix jacchus
100445390 Pongo abelii
100475834 Ailuropoda melanoleuca
100557771 Anolis carolinensis
100580430 Nomascus leucogenys
828209 Arabidopsis thaliana
538104 Bos taurus
10269 Homo sapiens
313564 Rattus norvegicus
230709 Mus musculus
334380 Danio rerio
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