anti-Zinc Finger Protein ZIC 1 (ZIC1) 抗体

ZIC1 encodes a member of the ZIC family of C2H2-type zinc finger proteins. 再加上,我们可以发ZIC1 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ZIC1 7545 Q15915
ZIC1 64618  
ZIC1 22771 P46684
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antibodies-online.cn销售最多的anti-ZIC1 抗体

Showing 10 out of 65 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ZIC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  ACHN cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB ZIC1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the ZIC1 antibody detected the ZIC1 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鼠 非结合性 ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.08 KDa) . Dilution: 1:500~1000 Detection limit for recombinant GST tagged ZIC1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 8至11个工作日
$461.00
详细
非结合性 ICC, IHC (fro), IF, IHC (p), IHC, WB Western Blot: Zic1 Antibody [ABIN153383] - WB analysis of Zic1 in overexpression lysate. 0.1 mL Log in to see 7至9个工作日
$444.19
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: ZIC1 Antibody  - Analysis in control (vector only transfected HEK293T lysate) and zIC1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells). Immunocytochemistry/Immunofluorescence: ZIC1 Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 WB ZIC1 Antibody (N-term)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ZIC1 antibody detected the ZIC1 protein (arrow). All lanes : Anti-ZIC1 Antibody (N-term) at 1:2000 dilution Lane 1: Jurkat whole cell lysates Lane 2: SH-SY5Y whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 IF, IHC (p), WB Immunohistochemistry (IHC) analyzes of Zic1/2/3 antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of Zic1/2/3 antibody in extracts from Jurkat cells. 0.1 mg Log in to see 6至8个工作日
$390.50
详细
非结合性 FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: ZIC1 Antibody (JA31-60)  - Analysis of paraffin-embedded mouse brain tissue using anti-Zic1 antibody. Counter stained with hematoxylin. Immunohistochemistry-Paraffin: ZIC1 Antibody (JA31-60)  - Analysis of paraffin-embedded rat brain tissue using anti-Zic1 antibody. Counter stained with hematoxylin. 100 μL Log in to see 34 Days
$373.75
详细
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (36.08 KDa) . 200 μL Log in to see 11至12个工作日
$440.00
详细

引用最多的anti-ZIC1 抗体

  1. Human Polyclonal ZIC1 Primary Antibody for ICC, IHC (fro) - ABIN153383 : Lipchina, Elkabetz, Hafner, Sheridan, Mihailovic, Tuschl, Sander, Studer, Betel: Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. in Genes & development 2011 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal ZIC1 Primary Antibody for ICC, IF - ABIN4366890 : Simões-Costa, McKeown, Tan-Cabugao, Sauka-Spengler, Bronner: Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is Encrypted in the genome. in PLoS genetics 2013 (PubMed)

更多抗ZIC1的相互作用对抗体

Human Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. Two proposed mechanisms for Zic-mediated cerebellar developmental control have been documented: regulation of neuronal progenitor proliferation-differentiation and the patterning of the cerebellar primordium. Clinical studies have also revealed that ZIC1 gain of function mutations contribute to coronal craniosynostosis, a rare skull malformation.

  2. By unbiased genome-wide DNA methylation (显示 HELLS 抗体) profiling and comprehensive stepwise verification and validation studies using in vitro and patient-derived samples, we identified 3 promising methylation markers (GHSR (显示 GHSR 抗体), SST (显示 SST 抗体), and ZIC1) associated with a 3q gain for the detection of cervical (pre)cancer

  3. down-regulated expression of ZIC1 contributed to the inhibition of cell proliferation, and inhibited the growth of tumor

  4. our results suggest that the Zic1 promoter methylation rate in plasma-derived DNA is of great significance for the early screening of gastric cancer and monitoring of tumorigenesis

  5. Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability.

  6. ZIC1 might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC.

  7. aberrant methylation is an important mechanism for ZIC1 inactivation in Hepatocellular carcinoma (HCC (显示 FAM126A 抗体)).

  8. ZIC1 is frequently inactivated by promoter hypermethyaltion and functions as a tumor suppressor in thyroid cancer through modulating PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) and MAPK (显示 MAPK1 抗体) signaling pathways and transcription factor FOXO3a (显示 FOXO3 抗体).

  9. Loss of ZIC1 expression is associated with malignant pleural mesothelioma.

  10. Methylation of ZIC1, a putative tumor suppressor, may be a novel determinant of ovarian cancer outcome

Xenopus laevis Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. snai2 and sox10 (显示 SOX10 抗体) expression was severely impaired upon manipulation of Znf703 (显示 ZNF703 抗体) expression levels in the embryo suggesting that Znf703 (显示 ZNF703 抗体) participates in neural crest formation downstream of Pax3 (显示 PAX3 抗体) and Zic1 (显示 ZIC5 抗体) in Xenopus

  2. Zic1 (显示 ZIC5 抗体), expressed at the anterior neural plate, is necessary and sufficient to promote placode fate.

  3. Pax3 (显示 PAX3 抗体) and Zic1 (显示 ZIC5 抗体) trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers.

  4. Pax3 (显示 PAX3 抗体) and Zic1 (显示 ZIC5 抗体) drive induction and differentiation of multipotent, migratory, and functional neural crest in Xenopus embryos.

  5. XMeis3 (显示 MEIS3 抗体) protein knock down also causes a loss of primary neuron and neural crest cell lineages, without altering expression of Zic, Sox (显示 PIPOX 抗体) or Pax3 (显示 PAX3 抗体) genes.

  6. Co-activation of Pax3 (显示 PAX3 抗体) and Zic1 (显示 ZIC5 抗体), in concert with Wnt (显示 WNT2 抗体), plays a decisive role for early neural crest determination in the correct place of the Xenopus ectoderm.

  7. These data suggest that interruption of BMP signaling facilitates neural determination via a complex mechanism, involving multiple regulatory factors that cooperate to control zic1 (显示 ZIC5 抗体) expression

  8. Zic1 (显示 ZIC5 抗体) directly upregulated the Xfeb gene during early neural development.

  9. Zic1 (显示 ZIC5 抗体) is an activator of Wnt (显示 WNT2 抗体) signaling.

  10. Data show that Pax3 (显示 PAX3 抗体) and Zic1 (显示 ZIC5 抗体) are necessary and sufficient to promote hatching gland and preplacodal fates, respectively, and that their combined activity is essential to specify the neural crest.

Mouse (Murine) Zinc Finger Protein ZIC 1 (ZIC1) interaction partners

  1. Geminin (显示 GMNN 抗体) and Zic1 could cooperatively activate the expression of several shared targets encoding transcription factors that control neurogenesis, neural plate patterning, and neuronal differentiation.

  2. Zic1 and Zic2 (显示 ZIC2 抗体) proteins are essential to control the balance between two defined neuron types in the postnatal forebrain.

  3. Brn2 (显示 POU3F2 抗体)-Zic1 axis is essential to specify neural fate in retinoic-acid-treated embryonic stem cells.

  4. Zic1 and Zic2 (显示 ZIC2 抗体) are required for coordinating mature neuronal gene expression patterns.

  5. Association with DNA-bound Pax3 (显示 PAX3 抗体) strengthens the ability of both Zic1 and Gli2 (显示 GLI2 抗体) to transactivate Myf5 (显示 MYF5 抗体) in the epaxial somite.

  6. Zic1 and Zic4 (显示 ZIC4 抗体) have both Shh (显示 SHH 抗体)-dependent and -independent roles during cerebellar development and multiple developmental disruptions underlie Zic1/4-related Dandy-walker malformation.

  7. Myf5 (显示 MYF5 抗体) activation in newly forming somites is delayed in Zic2 (显示 ZIC2 抗体) mutant embryos until the time of Zic1 activation, and both Zic2 (显示 ZIC2 抗体) and Myf5 (显示 MYF5 抗体) require noggin (显示 NOG 抗体) for their activation

  8. Zic1, a neural developmental transcription factor, plays an important role in shear flow mechanotransduction in osteocytes.

  9. findings suggest that Zic1 controls the expansion of neuronal precursors by inhibiting the progression of neuronal differentiation

  10. The functions of Zic1 and Zic3 (显示 ZIC3 抗体) may be essential to increasing neural cell numbers regionally in the medial telencephalon and to proper mediolateral patterning of the telencephalon.

ZIC1 抗原简介

蛋白简介

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

Gene names and symbols associated with ZIC1

  • Zic family member 1 (ZIC1) 抗体
  • Zic family member 1 (Zic1) 抗体
  • Zic family member 1 S homeolog (zic1.S) 抗体
  • zinc finger protein of the cerebellum 1 (Zic1) 抗体
  • opl 抗体
  • ZIC 抗体
  • ZNF201 抗体

Protein level used designations for ZIC1

Zic family member 1 (odd-paired homolog, Drosophila) , Zinc finger protein of the cerebellum 1 , zinc finger protein 201 , zinc finger protein ZIC 1 , zic protein member 1 , zinc finger protein of the cerebellum 1 , XZic1 , ZIC-r1 , ZIC-related protein 1 , Zic family member 1 (odd-paired homolog) , Zic-related-1 , xlZic1 , xopl , odd-paired homolog

GENE ID SPECIES
7545 Homo sapiens
64618 Rattus norvegicus
374103 Gallus gallus
399124 Xenopus laevis
22771 Mus musculus
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