anti-Zinc Finger Protein 148 (ZNF148) 抗体

Involved in transcriptional regulation. 再加上,我们可以发Zinc Finger Protein 148 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ZNF148 7707 Q9UQR1
ZNF148 22661 Q61624
ZNF148 58820 Q62806
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antibodies-online.cn销售最多的anti-Zinc Finger Protein 148 抗体

Showing 10 out of 60 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ZNF148 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Human Placenta 100 μL Log in to see 2至3个工作日
Cow 非结合性 IHC, WB WB Suggested Anti-ZNF148 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  OVCAR-3 cell lysate ZNF148 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells Rabbit Anti-ZNF148 Antibody       Paraffin Embedded Tissue:  Human alveolar cell   Cellular Data:  Epithelial cells of renal tubule  Antibody Concentration:   4.0-8.0 ug/ml  Magnification:   400X 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB Host:  Rabbit  Target Name:  Zfp148  Sample Type:  Mouse Heart lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
非结合性 EIA, WB 0.1 mL Log in to see 6至8个工作日
非结合性 IP, IHC, ELISA, WB Serum starvation induces ZBP-89 and p53 expression. AGS (gastric carcinoma) cells were cultured in serum-free F-12 medium for the indicated times, and western blots were used to detect the expression profiles of ZBP-89, p53, and p14ARF. Blotting was with  Rabbit-anti-ZBP-89 antibody. For detection use  HRP conjugated Gt-anti-Rabbit IgG MX10 . See Bai and Merchant (2001) for additional details. Anti-ZBP-89 antibody used to confirm siRNA knockdown of ZBP-89. See Bai and Merchant (2003) for additional details. 100 μL Log in to see 5至7个工作日
Cow 非结合性 IC, IF, IHC, WB Immunofluorescent analysis of ZNF148 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of ZNF148 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
非结合性 ELISA, ICC, IF, IHC, WB ABIN6267010 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis on HepG2 cell lysate using ZNF148 Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11至12个工作日
非结合性 IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using ZNF148 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ZNF148 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
非结合性 ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE ZNF148 antibody antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using ZNF148 antibody [N1N2], N-term, antibody at 1:250 dilution. 100 μL Log in to see 3至4个工作日
非结合性 ELISA, IF, IHC, WB 100 μL Log in to see Available

引用最多的anti-Zinc Finger Protein 148 抗体

  1. Human Polyclonal ZNF148 Primary Antibody for WB - ABIN1882015 : Udelhoven, Pasieka, Leeser, Krone, Schubert: Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter. in The Journal of endocrinology 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal ZNF148 Primary Antibody for IP, IHC - ABIN964672 : Ohneda, Ohmori, Ishijima, Nakano, Yamamoto: Characterization of a functional ZBP-89 binding site that mediates Gata1 gene expression during hematopoietic development. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal ZNF148 Primary Antibody for WB - ABIN2775856 : Chupreta, Brevig, Bai, Merchant, Iñiguez-Lluhí: Sumoylation-dependent control of homotypic and heterotypic synergy by the Kruppel-type zinc finger protein ZBP-89. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal ZNF148 Primary Antibody for ICC, IF - ABIN4367002 : Sayin, Nilton, Ibrahim, Ågren, Larsson, Petit, Hultén, Ståhlman, Johansson, Bergo, Lindahl: Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment. in PLoS ONE 2013 (PubMed)

更多抗Zinc Finger Protein 148的相互作用对抗体

Human Zinc Finger Protein 148 (ZNF148) interaction partners

  1. ZNF148(FL) could increase proliferation, invasion, and migration of colorectal cancer cells, while ZNF148(DeltaN) showed opposite effect; the two splicing isoforms of ZNF148 may exert a mutual antagonistic effect to each other on the malignant biological activities.

  2. Downregulation of ZNF148 drives the formation of a muscle phenotype with rapid expression of myosin heavy chain, even in proliferative conditions. This phenotype was most likely mediated by the robust and swift upregulation of MYOD and MEF2C.

  3. ZBP-89 is a potential tumor suppressor in hepatocellular carcinoma (HCC) and it can inhibit the growth of HCC via multiple channels; higher expression of ZBP-89 may predict better survivals and lower recurrence of HCC patients

  4. Our findings suggested that ZBP-89 and Sp1 overexpression induced Bak expression in a genetic manner. Increased Bak level was associated with poor patient survival, whereas high level of Sp1 is a beneficial factor for patient survival.

  5. The results indicate that the association with chr5p15.33-Region 2 may be explained by rs36115365, a variant influencing TERT expression via ZNF148 in a manner consistent with elevated TERT in carriers of the C allele.

  6. ZNF148 as a gene involved in a newly described intellectual disability syndrome with a recurrent phenotype and postulate that the ZNF148 is a hitherto unrecognized but crucial transcription factor in the development of the corpus callosum.

  7. A larger role ZBP-89 plays in gene regulation during inflammation.ZBP-89 regulates of MMP-1 expression.ZBP-89 and NF-kappaB appear to bind cooperatively on both promoters.

  8. ZBP-89 attenuates HDAC3 by increasing IkappaB degradation, dependent on Pin1 but independent of NF-Kappab

  9. zinc-binding protein-89 upregulates the expression of Bak by targeting multiple components of the epigenetic pathway in hepatocellular carcinoma.

  10. lower expression of ZNF148 in colorectal cancer was significantly associated with worse clinicopathologic variables, including lymph node metastases, poor differentiation, and a higher rate of disease recurrence

  11. this study provides vigorous evidence that ZBP-89 was significantly downregulated in clear cell renal cell carcinoma(CCRCC) and could be served as a promising biomarker for prediction of distal metastasis and prognosis of patient with CCRCC.

  12. Colony formation was reduced dramatically in those hepatocellular carcinoma cell lines in which ZBP-89 overexpression was demonstrated; this appeared to correlate with increased apoptosis.

  13. We found that the TP53-G245D variant but not TP53-R249S abrogated HDAC inhibitor p21 induction by binding to ZBP-89 and retaining it in the cytoplasm.

  14. ZBP-89 is a regulator of Pdcd4 gene, binding to the basal promoter either alone or by interacting with Sp family members.

  15. An activating role for ZBP-89 in human globin gene regulation and erythroid differentiation.

  16. Alternative binding of ZBP89 or SP1 to the described region in the IRS2 promoter regulates neuronal IRS2 expression in a PI3K-dependent manner.

  17. ZBP-89 is a repressor of the human beta 2-integrin CD11b gene during differentiation of monocytes into macrophages

  18. ZBP-89 co-localized with p53 in the nucleus in about 67% (12 of 18) of all cases positive for the nuclear p53 protein, suggesting that ZBP-89 may play a role in the nuclear accumulation of the p53 protein in a subset recurrent hepatocellular carcinoma.

  19. interaction of Stat3 and ZBP-89 may be crucial for overcoming the effects of the repressor ZBP-89, which suggests a novel mode for Stat3 gene activation.

  20. ZBP-89-mediated apoptosis occurs via a p53-independent mechanism that requires JNK activation.

Mouse (Murine) Zinc Finger Protein 148 (ZNF148) interaction partners

  1. Data indicate zinc finger protein 148 (ZFP148) as a transcription factor that differentially binds to the zinc finger protein 30 protein (Zfp30) promoter region harboring rs51434084.

  2. The results suggest that Zfp148 controls the fate of newly transformed intestinal tumor cells by repressing p53 and that targeting Zfp148 might be useful in the treatment of colorectal cancer.

  3. Study demonstrated that miR-20b suppressed ZFP-148 expression by directly binding to the 3'-UTR of target mRNA and repressed translation at posttranscriptional level during virus myocarditis.

  4. Zfp148 deficiency increases p53 activity and protects against atherosclerosis by causing proliferation arrest of lesional macrophages.

  5. These data identify an important role for ZBP-89 in regulating stress hematopoiesis in adult mouse bone marrow.

  6. Results indicate that Zfp148-deficient mice generate normal mature hematopoietic populations.

  7. Zfp148 deficiency causes lung maturation defects and lethality.

  8. ZBP-89 is required for expression of the Tph1 gene and subsequent production of 5HT in response to bacterial infection in mice. Reductions in epithelial ZBP-89 increase susceptibility to colitis and sepsis after infection with S. typhimurium.

  9. MiR-203 expression downregulated ZFP-148 mRNA translation by specifically targeting its 3' UTR, which resulted in differential expression of its downstream target genes, which in turn promote cell survival to foster Coxsackievirus B3 replication

  10. ataxia telangiectasia mutated protein phosphorylation of ZBP-89 contributes to Histone deacetylase inhibitors induction of p21(waf1) gene expression

  11. identify ZBP-89 as being a novel transcription factor involved in erythroid and megakaryocytic development and suggest that it serves a cooperative function with GATA-1 and/or FOG-1 in a developmental stage-specific manner

  12. The transcriptional repressor ZBP-89 and the lack of Sp1/Sp3, c-jun and Stat3 are important for the down-regulation of the vimentin gene during C2C12 myogenesis.

  13. the G(5) string is necessary for Gata1 gene expression in vivo and ZBP-89 is the functional trans-acting factor for this cis-acting region.

Zebrafish Zinc Finger Protein 148 (ZNF148) interaction partners

  1. identify ZBP-89 as being a novel transcription factor involved in erythroid and megakaryocytic development and suggest that it serves a cooperative function with GATA-1 and/or FOG-1 in a developmental stage-specific manner

Zinc Finger Protein 148 (ZNF148) 抗原简介


Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.

Gene names and symbols associated with ZNF148

  • zinc finger protein 148 (ZNF148) 抗体
  • zinc finger protein 148 (Zfp148) 抗体
  • zinc finger protein 148 (znf148) 抗体
  • 2210405J08Rik 抗体
  • AI480666 抗体
  • AW045217 抗体
  • BERF-1 抗体
  • BFCOL1 抗体
  • fb06h05 抗体
  • HT-BETA 抗体
  • pHZ-52 抗体
  • SLC12A8 抗体
  • wu:fb06h05 抗体
  • Zbp-89 抗体
  • ZFP148 抗体
  • zfp149 抗体
  • zgc:165342 抗体
  • Znf148 抗体

Protein level used designations for ZNF148

CACCC box-binding protein , CLL-associated antigen KW-10 , transcription factor ZBP-89 , zinc finger DNA-binding protein 89 , G-rich box-binding protein , beta enolase repressor factor 1 , transcription factor BFCOL1 , zinc finger binding protein 89 , zinc finger DNA binding protein 89 , solute carrier family 12 (potassium/chloride transporters), member 8 , zinc finger protein 148 (pHZ-52)

7707 Homo sapiens
22661 Mus musculus
58820 Rattus norvegicus
488017 Canis lupus familiaris
613265 Bos taurus
560300 Danio rerio
424259 Gallus gallus
100447276 Pongo abelii
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